Evidence map›Paper›PMID 41622272›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Impact of intermittent pneumatic compression stockings on pulmonary embolism rates after laryngectomy: A retrospective Before-After comparative study.

Felix Johnson, Felix Keller, Hannes Thomas Fischer, Nora-Maria Burian, Anna Stenzl, Wegene Borena, Fayez El Hachem, Barbara Wollenberg, Susanne Trainotti, Benedikt Hofauer

Abstract readComparative Study
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Felix JohnsonUniversity Hospital for Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Anichstraße 35, Innsbruck, A-6020, Austria.
Felix KellerDepartment of Internal Medicine IV, Nephrology and Hypertension, Medical University Innsbruck, Innsbruck, Austria.ORCID http://orcid.org/0000-0002-8240-7255
Hannes Thomas FischerUniversity Hospital for Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Anichstraße 35, Innsbruck, A-6020, Austria. Hannes.fischer@tirol-kliniken.at.ORCID http://orcid.org/0009-0001-9762-7656
Nora-Maria BurianUniversity Hospital for Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Anichstraße 35, Innsbruck, A-6020, Austria.
Anna StenzlUniversity Hospital for Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Anichstraße 35, Innsbruck, A-6020, Austria.
Wegene BorenaInstitute of Virology and Department for Hygiene, Microbiology, and Public Health, Medical University of Innsbruck, Anichstraße 35, Innsbruck, A-6020, Austria.
Fayez El HachemDepartment of Otorhinolaryngology, Head and Neck Surgery, Klinikum rechts, Isar Technical University of Munich (TUM School of Medicine), Munich, Germany.
Barbara WollenbergDepartment of Otorhinolaryngology, Head and Neck Surgery, Klinikum rechts, Isar Technical University of Munich (TUM School of Medicine), Munich, Germany.
Susanne TrainottiDepartment of Otorhinolaryngology, Head and Neck Surgery, Klinikum rechts, Isar Technical University of Munich (TUM School of Medicine), Munich, Germany.
Benedikt HofauerUniversity Hospital for Otorhinolaryngology, Head and Neck Surgery, Medical University of Innsbruck, Anichstraße 35, Innsbruck, A-6020, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTotal laryngectomy is a common procedure for laryngeal and hypopharyngeal carcinoma, but due to its long surgical duration and the underlying malignancy it is linked to a high incidence of pulmonary embolism (PE) and other thromboembolic events, affecting clinical outcomes. This study aimed to compare the impact of perioperative intermittent pneumatic compression stockings (IPCS) and medical thrombosis prophylactic stockings (MTPS) on thromboembolic incidence.

methodsThis single-center retrospective study included 98 patients who underwent total laryngectomy between March 2018 and March 2024. Patient records and an electronic database were reviewed for thromboembolic events. From March 2021 onward, IPCS replaced MTPS, enabling a before-after comparison. To assess the effect of IPCS on PE, an inverse probability of treatment weighted (IPTW) logistic regression model was used, accounting for comorbidities and perioperative risk factors.

resultsIn our cohort, 13 patients (13%) developed pulmonary embolism (PE). A history of thromboembolic events significantly increased PE risk (OR 17.8, p = 0.015). Postoperative bleeding occurred in 5.1% of patients and was associated with a higher PE incidence. IPCS use significantly reduced PE risk (adjusted OR 0.0508, unadjusted OR 0.1080) in the IPTW model.

conclusionsIPCS significantly reduced PE risk compared to MTPS, indicating definite prophylactic benefits. Patients with a history of thromboembolic events are at higher risk for PE after laryngectomy, which also increases the risk of postoperative bleeding and reoperation due to the required anticoagulation.

Indexed as

Intermittent Pneumatic Compression DevicesLaryngeal NeoplasmsLaryngectomyPostoperative ComplicationsPulmonary EmbolismStockings, CompressionAgedFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk FactorsAnticoagulationIntermittent pneumatic compressionLaryngectomyPerioperative risk factorsPulmonary embolismThromboembolic eventThrombosis

Identifiers

PMID41622272

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.