Evidence map›Paper›PMID 41622203›Full record

ArticleCardiovascular diabetology. Endocrinology reports2026

Prevalence and association of metabolic syndrome components with benign prostate hyperplasia.

Hundesa Emana Urgesa, Tesfaye Adugna Leta, Teka Obsa Feyisa, Amanuel Hika Bati, Kassa Tefera Tulu, Bedasa Addisu Nasi, Zerihun Aseffa Tereffe

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Article in Cardiovascular diabetology. Endocrinology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Hundesa Emana UrgesaDepartment Medical Biochemistry, School of Medicine, College of Health Science, Haramaya University, Harar, Ethiopia. hundesaemana5@gmail.com.ORCID http://orcid.org/0009-0001-4846-3210
Tesfaye Adugna LetaDepartment of Biomedical Sciences, Jimma University, Jimma, South West Ethiopia, Ethiopia.
Teka Obsa FeyisaDepartment Medical Biochemistry, School of Medicine, College of Health Science, Haramaya University, Harar, Ethiopia.
Amanuel Hika BatiSchool of Medical Laboratory, Institute of Health Sciences, Wallaga University, Nekemte, Oromia, Ethiopia.
Kassa Tefera TuluDepartment of Biomedical Science, School of Medicine, Institute of Health, Bule Hora University, Hagere Mariam, Ethiopia.
Bedasa Addisu NasiDepartment of Medical Laboratory Science, School of Medicine, College of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia.
Zerihun Aseffa TereffeDepartment of Biomedical Sciences, Jimma University, Jimma, South West Ethiopia, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBenign prostate hyperplasia (BPH) is a non-cancerous enlargement of both glandular and epithelial tissue of the prostate. The disease affects a significant portion of older ages, particularly those above 40 years old. It is thought that in addition to age, there is a contribution of metabolic syndrome (Mets) to the pathogenesis of BPH. There is scanty of study regarding to association of MetS with BPH, So this study is primarily intended to assess the association of MetS with BPH among patients attending Jimma University Medical Center (JUMC). METHODS AND MATERIALS: A hospital-based cross-sectional study design was employed among 158 BPH patients attending JUMC, the subjects were selected consecutively, and all socio-demographic variables were collected by trained nurses after informed consent was obtained. Biochemical data were collected by laboratory technologists. Before analysis, daily quality control was checked. The collected data were entered into epi-data 4.6.0.6 checked, cleaned, and exported into SPSS version 26 for analysis. All descriptive variables were shown using tables, figures, and charts. After checking all assumptions of logistic regression, analysis was conducted at a significant value of 0.05.

resultsOur study found that the overall prevalence of metabolic syndrome among BPH patients was 38.6% (0.31,0.46). Among the components, low HDL comprises a high proportion following high blood glucose, elevated TG, and hyperglycemia respectively. Regarding factors associated with enlargement of the prostate, fasting blood glucose, obesity, and low HDL were significantly associated with large prostate volume (enlargement of the prostate).

conclusionAccording to our study, components of metabolic syndrome are the predictor variables for the enlargement of the prostate gland highlighting the importance of early diagnosis and treatment to alleviate further complications.

Indexed as

BPHEthiopiaJUMCMetabolic syndrome componentsProstate enlargement

Identifiers

PMID41622203
PMCPMC12862902

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