Evidence map›Paper›PMID 41622181›Full record

ArticleBMC geriatrics2026

Facilitators and barriers to volume management interventions in patients with heart failure and hyponatremia: a qualitative study.

Hua Chen, Huiyan Chen, Yingxia Yao, Mengdie Liu, Xiaoyun Xiong

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Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Hua Chen *The Second Affiliated Hospital of Nanchang University, No. 1 Minde/Mingde Road, Donghu District, Nanchang, 330006, China.
Huiyan Chen *The Second Affiliated Hospital of Nanchang University, No. 1 Minde/Mingde Road, Donghu District, Nanchang, 330006, China.
Yingxia YaoThe Second Affiliated Hospital of Nanchang University, No. 1 Minde/Mingde Road, Donghu District, Nanchang, 330006, China.
Mengdie LiuThe Second Affiliated Hospital of Nanchang University, No. 1 Minde/Mingde Road, Donghu District, Nanchang, 330006, China.
Xiaoyun XiongThe Second Affiliated Hospital of Nanchang University, No. 1 Minde/Mingde Road, Donghu District, Nanchang, 330006, China. xxy6692@163.com.

Funding

Jiangxi Province graduate student innovation project YC2024-B055the Chinese Nursing Association ZHKY202321the National Natural Science Foundation 72464022
6 · The paper itself

Abstract

backgroundHeart failure is highly prevalent among older adults, and volume management is central to both medical treatment and nursing care. Patients with concomitant hyponatremia often require tailored, hyponatremia-sensitive strategies; however, such personalized approaches are variably implemented in routine practice.

methodsQualitative interviews guided by the Consolidated Framework for Implementation Research (CFIR 2.0) were conducted with 12 healthcare professionals, 10 patients with heart failure and hyponatremia, and 10 caregivers. Data collection continued until data saturation was reached, defined as no new themes emerging in three consecutive interviews. Data were analyzed using thematic analysis.

resultsWe identified three facilitator themes: (1) tailored targets and support that make volume management workable; (2) alignment of individualized targets with existing heart failure workflows; and (3) hyponatremia awareness and belief in the value of implementation. We also identified four barrier themes: (1) limited access to trusted, actionable evidence that undermines hyponatremia-sensitive volume management; (2) gaps in discharge preparation and care transitions that disrupt continuity across care settings; (3) awareness alone, without sufficient capability, that limits practical execution; and (4) geriatric constraints and limited support capacity that hinder sustained implementation.

conclusionsBy synthesizing the identified facilitators and barriers, we found that volume management for patients with heart failure and hyponatremia represents a more individualized, dynamic, and precise approach than routine volume management. The barriers helped clarify current gaps in hyponatremia-sensitive volume management and informed multi-level strategies to address them. These findings provide a theoretical foundation for optimizing volume management in patients with heart failure complicated by hyponatremia in clinical practice.

trial registrationThe trial was registered at the Chinese Clinical Trial Registry under the identifier ChiCTR2400089084 on September 2, 2024.

Indexed as

Heart FailureHyponatremiaAgedAged, 80 and overDisease ManagementFemaleHumansMaleMiddle AgedQualitative ResearchBarriers and facilitatorsChronic diseaseHeart failureHyponatremiaImplementation scienceQualitative researchVolume management

Identifiers

PMID41622181
PMCPMC12952140

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.