Evidence map›Paper›PMID 41621882›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Ultrasound Contrast between the Trapezius and Supraspinatus Muscles as a Potentially Specific Finding of Facioscapulohumeral Muscular Dystrophy.

Isamu Yamakawa, Ryota Tamura, Hiroyuki Yabata, Takahito Tsukamoto, Shuhei Kobashi, Yoshitaka Tamaki, Nobuhiro Ogawa, Akihiro Kitamura, Makoto Urushitani

Abstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Isamu YamakawaDepartment of Neurology, Shiga University of Medical Science, Japan.
Ryota TamuraDepartment of Neurology, Shiga University of Medical Science, Japan.
Hiroyuki YabataDepartment of Neurology, Shiga University of Medical Science, Japan.
Takahito TsukamotoDepartment of Neurology, Shiga University of Medical Science, Japan.
Shuhei KobashiDepartment of Neurology, Shiga University of Medical Science, Japan.
Yoshitaka TamakiDepartment of Neurology, Shiga University of Medical Science, Japan.
Nobuhiro OgawaDepartment of Neurology, Shiga University of Medical Science, Japan.
Akihiro KitamuraDepartment of Neurology, Shiga University of Medical Science, Japan.
Makoto UrushitaniDepartment of Neurology, Shiga University of Medical Science, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Facioscapulohumeral muscular dystrophy (FSHD) demonstrates selective muscle involvement, with trapezius muscle affected and rotator cuff muscles relatively preserved in the shoulder girdle. While magnetic resonance imaging of this pattern has been documented, the diagnostic utility of ultrasound remains unclear. This study aimed to determine whether an ultrasound echogenicity analysis can identify this selective involvement pattern in FSHD. Methods This single-center retrospective study examined ultrasound echogenicity differences between the trapezius and supraspinatus muscles in three genetically confirmed FSHD type 1 patients and nine disease controls with shoulder weakness. The trapezius-to-supraspinatus echogenicity difference was calculated, and statistically compared using the Mann-Whitney U test. Results FSHD patients demonstrated significantly higher trapezius-to-supraspinatus echogenicity differences (mean±SD: 113±26) compared to controls (36±11; p<0.05). All three FSHD patients showed values exceeding the control range, with complete separation between the two groups observed. Conclusions Ultrasound may non-invasively detect the characteristic muscle selectivity pattern of FSHD and could serve as a diagnostic adjunct prior to genetic testing.

Indexed as

Muscular Dystrophy, FacioscapulohumeralRotator CuffSuperficial Back MusclesAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesUltrasonographydiagnostic imagingechogenicityfacioscapulohumeral muscular dystrophymuscle selectivityultrasound

Identifiers

PMID41621882
PMCPMC13668789

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.