Evidence map›Paper›PMID 41621867›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Transcatheter Mitral Edge-to-edge Repair in Patients with Transthyretin Cardiac Amyloidosis: A Four-case Series.

Ayaka Ujita, Masayoshi Yamamoto, Tomoya Hoshi, Kentaro Minami, Yu Yamada, Kimi Sato, Tomoko Machino-Ohtsuka, Tomoko Ishizu

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PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ayaka UjitaDepartment of Cardiology, Institute of Medicine, University of Tsukuba, Japan.
Masayoshi YamamotoDepartment of Cardiology, Institute of Medicine, University of Tsukuba, Japan.
Tomoya HoshiDepartment of Cardiology, Institute of Medicine, University of Tsukuba, Japan.
Kentaro MinamiDepartment of Cardiology, Institute of Medicine, University of Tsukuba, Japan.
Yu YamadaDepartment of Cardiology, Institute of Medicine, University of Tsukuba, Japan.
Kimi SatoDepartment of Cardiology, Institute of Medicine, University of Tsukuba, Japan.
Tomoko Machino-OhtsukaDepartment of Cardiology, Institute of Medicine, University of Tsukuba, Japan.
Tomoko IshizuDepartment of Cardiology, Institute of Medicine, University of Tsukuba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac amyloidosis is characterized by the deposition of amyloid fibrils, which cause complications such as mitral regurgitation (MR). The efficacy of transcatheter mitral edge-to-edge mitral repair (TEER) in patients with amyloidosis remains uncertain. We herein present four cases of TEER for transthyretin cardiac amyloidosis. TEER reduced the MR in all cases. However, two of the four individuals died within one year, and in one case, a recurrent MR deterioration occurred. Although TEER can reduce MR in individuals with cardiac amyloidosis, the long-term outcomes appear to be poor owing to disease progression or comorbidities, thereby underscoring the need for careful patient selection.

Indexed as

Amyloid Neuropathies, FamilialMitral ValveMitral Valve InsufficiencyHumansTreatment Outcomecardiac amyloidosismitral regurgitationtranscatheter edge-to-edge repairtransthyretin amyloidosis

Identifiers

PMID41621867
PMCPMC13627472

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.