Evidence map›Paper›PMID 41621815›Full record

ArticleBJPsych open2026

Effects of HPV-related psychosocial burden and general psychological health on quality of life and sexual function in women with HPV infection in the initial period after diagnosis.

Sofia Boukouvala, Themistoklis Loukopoulos, Antonios Athanasiou, Maria Kyrgiou, Minas Paschopoulos, Evangelos Paraskevaidis, Vassiliki Siafaka

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Article in BJPsych open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Sofia BoukouvalaUniversity Hospital of Ioannina, Ioannina, Greece.
Themistoklis LoukopoulosDepartment of Obstetrics & Gynaecology, University Hospital of Ioannina, Ioannina, Greece.
Antonios AthanasiouDepartment of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, London, UK.
Maria KyrgiouDepartment of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, London, UK.
Minas PaschopoulosDepartment of Obstetrics & Gynaecology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Evangelos ParaskevaidisDepartment of Obstetrics & Gynaecology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Vassiliki SiafakaSchool of Health Sciences, University of Ioanninahttps://ror.org/01qg3j183, Ioannina, Greece.ORCID https://orcid.org/0000-0002-8002-8825

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman papillomavirus (HPV) infection has a negative impact on quality of life (QoL) and sexual function, mainly owing to increased levels of anxiety and distress.

aimsTo examine the potentially moderating effects of general psychological health on the relationships between (a) HPV-related psychosocial burden and QoL and (b) HPV-related psychosocial burden and sexual function.

methodThe HPV Impact Profile, Female Sexual Function Index, General Health Questionnaire-28 and Life Satisfaction Inventory questionnaires were completed by 151 women.

resultsHPV-related psychosocial burden and general psychological health accounted for 23.2% of QoL variability. There was not strong evidence for a moderating effect of general psychological health on the relationship between HPV-related psychosocial burden and QoL. Higher HPV-related psychosocial burden predicted worse sexual function on average. However, HPV-related psychosocial burden accounted for only 4.1% of sexual function variability.

conclusionsHigher HPV-related psychosocial burden is associated with lower QoL as well as worse sexual function. General psychological health predicts changes in QoL over and above HPV-related psychosocial burden; thus, a deep understanding of emerging mental health issues soon after diagnosis is crucial to improve counselling and enhance women's mental empowerment to achieve a better psychological response.

Indexed as

initial periodpsychological distressquality of lifesexual functionWomen with HPV

Identifiers

PMID41621815
PMCPMC12926894

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