SynthesisJournal of cachexia, sarcopenia and muscle2026
Physical Activity Improves Quality of Life in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.
Synthesis in Journal of cachexia, sarcopenia and muscle, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Physical Activity Improves Quality of Life in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.Journal of cachexia, sarcopenia and muscle · 2026Pooled it
- Reversal of Frailty and Improvement in Quality of Life Following Advanced Therapy Initiation in Patients with Inflammatory Bowel Disease: A Prospective Cohort Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Factors associated with kinesiophobia in patients with inflammatory bowel disease: associations with functional independence and fatigue.Frontiers in medicine · 2026Article
- Association between physical activity and inflammatory bowel disease: a prospective cohort study.Frontiers in public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
backgroundPatients with inflammatory bowel disease (IBD) are often less active physically and experience impaired bone mineral density (BMD) as well as sarcopenia, which are associated with a higher risk of poor disease outcomes. Physical exercise can improve BMD and sarcopenia and may also play a role in controlling inflammation via anti-inflammatory myokines. This study aimed to evaluate the effects of structured physical exercise on the disease activity and quality of life of patients with IBD by conducting a before-and-after analysis.
methodsWe conducted a systematic search on 16 November 2023. Studies with structured exercise interventions in patients with IBD focusing on quality of life, disease activity, body composition, muscle strength, inflammatory markers, aerobic fitness and sedentary time were included. The mean difference (MD) or the standardized MD (SMD) of the differences between the before and after values was used to measure the effect size with a 95% confidence interval (CI). Risk of bias was assessed using the MINORS tool.
resultsTwenty-one studies involving 498 patients with IBD were included. Quality of life improved significantly: SMD 0.55 (CI, 0.30-0.80), particularly in the systemic subscale. Disease activity scores showed a non-significant improvement: SMD -0.20 (CI, -0.47 to 0.07) in Crohn's disease and SMD -0.23 (CI, -0.46 to 0.00) in ulcerative colitis. Numbers of inflammatory markers and faecal calprotectin levels also improved, but not significantly. Muscle strength and aerobic fitness improved, with a significant increase in VO
conclusionRegular physical activity improves quality of life and physical fitness of IBD patients, with potential benefits for disease activity and sarcopenia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.