Evidence map›Paper›PMID 41621811›Full record

ArticleBJPsych open2026

Cost-effectiveness of targeted feedback interventions after depression screening in primary care: health economic evaluation of the GET.FEEDBACK.GP trial.

Léon G Kreis, Hans-Helmut König, Sebastian Kohlmann, Bernd Löwe, Martin Scherer, Christian Brettschneider

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Article in BJPsych open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Léon G KreisDepartment of Health Economics and Health Services Research, https://ror.org/01zgy1s35University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID https://orcid.org/0009-0006-7309-3692
Hans-Helmut KönigDepartment of Health Economics and Health Services Research, https://ror.org/01zgy1s35University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Sebastian KohlmannDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Bernd LöweDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID https://orcid.org/0000-0003-4220-3378
Martin SchererInstitute of Primary Medical Care, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Christian BrettschneiderDepartment of Health Economics and Health Services Research, https://ror.org/01zgy1s35University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepression screening in primary care has been widely discussed, but its economic implications have remained largely unexplored. The GET.FEEDBACK.GP randomised controlled trial evaluated feedback interventions after depression screening in primary care. The study arms were (a) feedback provided to the general practitioner; (b) feedback to both the patient and the treating general practitioner; and (c) a control group without feedback. Analysis of clinical effectiveness revealed that feedback interventions were not associated with decreased depression severity. Their economic implications were the subject of this study.

aimsTo evaluate the economic impact of general-practitioner- and patient-targeted feedback following depression screening for adults in German primary care.

methodA cost-effectiveness analysis from a societal perspective of feedback interventions after depression screening with a time horizon of 12 months was conducted. Direct and indirect costs were estimated. Quality-adjusted life years were calculated on the basis of the EQ-5D-5L, and incremental cost-effectiveness ratios and cost-effectiveness acceptability curves based on the net monetary benefit were constructed. Sensitivity analyses and

resultsIn total, 987 participants who screened positive for at least moderate depression were included. Feedback provision was not significantly associated with changes in costs or quality-adjusted life years during follow-up. Cost-effectiveness probabilities of feedback interventions were lower than 50% compared with no feedback. Higher cost-effectiveness probabilities were observed in patients whose suspected depression was confirmed 1 month post-screening and in those with previous depression.

conclusionsThe analysed feedback interventions cannot be considered to be cost-effective for the investigated population. Patient-targeted feedback was potentially cost-effective for subpopulations, particularly patients with a later confirmed depression diagnosis; this requires further research.

Indexed as

cost-effectivenessDepression screeningfeedback interventionhealth economic evaluationprimary care

Identifiers

PMID41621811
PMCPMC12926889

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