Evidence map›Paper›PMID 41621484›Full record

ArticleClinical medicine (London, England)2026

Prolonged disorders of consciousness: Practice described by palliative and rehabilitation physicians.

Mary Miller, Tim Harrison, Siobhan Barrie, Anton Pick

Abstract read
In one paragraph

Article in Clinical medicine (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frailty, fragility and falls in older people: What's new?Clinical medicine (London, England) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mary MillerConsultant palliative medicine, Department of palliative care, Sir Michael Sobell House, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7LE, UK; Honorary senior clinical lecturer, Nuffield Department of Medicine, University of Oxford, Old Road Campus, Oxford OX3 7BN, UK. Electronic address: Mary.miller@ouh.nhs.uk.
Tim HarrisonConsultant palliative medicine, Department of palliative care, Sir Michael Sobell House, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7LE, UK. Electronic address: Tim.harrison@ouh.nhs.uk.
Siobhan BarrieConsultant in Rehabilitation Medicine, Oxford Centre for Enablement, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7LE, UK.
Anton PickConsultant in Rehabilitation Medicine, Oxford Centre for Enablement, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7LE, UK. Electronic address: Anton.pick@ouh.nhs.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectiveNational clinical guidelines for the management of prolonged disorders of consciousness (PDOC) following sudden-onset brain injury were updated in 2020. Since then, clinical experience has grown. This paper reports on current practice. STUDY

designA questionnaire was developed, tested and sent to rehabilitation and palliative medicine specialists, via the British Society of Physical and Rehabilitation Medicine and Association for Palliative Medicine. Anonymised responses were analysed.

results63.5% (n = 61) of respondents were involved in the care of people with PDOC, with two-thirds working in palliative medicine. 44% of clinicians withdraw clinically assisted nutrition and hydration (CANH) in the patient's usual place of care. Where a decision to admit is taken, 43% will admit to a hospice inpatient unit. 87% of respondents do not arrange long line or central intravenous access prior to withdrawal of CANH. Ninety-five per cent of clinicians prescribe opioids and 92% prescribe sedatives for prn use or directly convert regular medications to a continuous subcutaneous infusion when withdrawing CANH. Most clinicians titrate according to need. In 81% of cases, there was no difficulty with symptom management on withdrawal of CANH. Forty-eight per cent of respondents worked with staff who expressed a conscientious objection to CANH, 40% in palliative medicine.

conclusionNational guidance should be updated to reflect clinical practice with regard to place of care, the effectiveness of a subcutaneous route and the use of proportionate symptom management.

Indexed as

Consciousness DisordersPalliative CarePractice Patterns, Physicians'HumansSurveys and QuestionnairesDisorders of consciousnessEnd-of-lifePalliative carePDOCSymptom management

Identifiers

PMID41621484
PMCPMC12925495

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.