ArticleWorld journal of urology2026
Pelvic floor electromyographic dysfunction as a novel physiological indicator for subclassifying sexual dysfunction in patients with chronic prostatitis/chronic pelvic pain syndrome.
Article in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundSexual dysfunction (SD) is a common complication in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), and there remains a lack of objective diagnostic physiological indicators in clinical practice.
objectiveThis study aimed to explore the value of pelvic floor electromyography (PF-EMG) parameters as novel physiological indicators for SD in CP/CPPS patients.
methodsA total of 116 CP/CPPS patients were enrolled and stratified into PE and ED subgroups based on validated questionnaires (C-ISFPE and IIEF-5). All participants underwent standardized PF-EMG assessment to evaluate resting tone, fast-twitch, and slow-twitch functions. Statistical analyses included t-tests, logistic regression, and ROC curve analysis.
resultsIn the PE subgroup (n = 66), resting tone was significantly elevated (anterior baseline: 6.49 ± 3.42 µV vs. 3.78 ± 2.79 µV in the non-PE group, P < 0.001) and served as an independent predictor of PE (OR = 1.428, P = 0.003). In the ED subgroup (n = 45), fast-twitch function was severely impaired (rapid contraction: 37.87 ± 18.36 µV vs. 69.92 ± 25.78 µV in the non-ED group, P < 0.001). With a cut-off value of < 45.41 µV for rapid contraction, the area under the curve (AUC) for ED diagnosis was 0.866, with a sensitivity of 92.6%.
conclusionPF-EMG parameters serve as objective, non-invasive physiological indicators that can effectively distinguish between PE and ED subtypes in CP/CPPS patients, paving the way for targeted therapies.
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