Evidence map›Paper›PMID 41620960›Full record

ArticleAlcohol, clinical & experimental research2026

Self-help group participation, avoidance of nonalcoholic beer, and nonsmoking independently predict better drinking outcomes in Japanese alcohol-dependent men.

Akira Yokoyama, Mitsuru Kimura, Atsushi Yoshimura, Junichi Yoneda, Hitoshi Maesato, Yasunobu Komoto, Hideki Nakayama, Hiroshi Sakuma, Yosuke Yumoto, Tsuyoshi Takimura and 5 more

Abstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Akira YokoyamaNational Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan.ORCID https://orcid.org/0000-0003-1869-1359
Mitsuru KimuraNational Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan.
Atsushi YoshimuraDivision of Psychiatry, Tohoku Medical and Pharmaceutical University, Sendai, Japan.ORCID https://orcid.org/0000-0003-1995-8190
Junichi YonedaNational Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan.
Hitoshi MaesatoDepartment of Psychiatry, National Hospital Organization Ryukyu Hospital, Kunigami, Japan.
Yasunobu KomotoDepartment of Psychiatry, Yoshino Hospital, Tokyo, Japan.
Hideki NakayamaDepartment of Psychiatry, Asahiyama Hospital, Sapporo, Japan.
Hiroshi SakumaDepartment of Psychiatry, National Hospital Organization Saigata Medical Center, Joetsu, Japan.
Yosuke YumotoNational Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan.
Tsuyoshi TakimuraNational Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan.
Tomomi ToyamaNational Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan.
Takeshi MizukamiNational Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan.
Tetsuji YokoyamaDepartment of Health Promotion, National Institute of Public Health, Wako, Japan.
Susumu HiguchiNational Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan.
Sachio MatsushitaNational Hospital Organization Kurihama Medical and Addiction Center, Yokosuka, Japan.

Funding

Health Labor Sciences Research Grant, Japan H26-seishin-ippan-006Intramural Research Grant for Neurological and Pshychiatric Disorders of NCNP, Japan 25-2
6 · The paper itself

Abstract

backgroundRelapse after inpatient treatment for alcohol dependence is a major barrier to recovery. This study evaluated one-year drinking outcomes and their associations with self-help group participation, nonalcoholic beer use, smoking after discharge, and other prognostic factors among Japanese men treated for alcohol dependence.

methodsWe conducted a prospective 12-month follow-up of 198 male patients who completed a three-month inpatient program in 2014. Drinking status, self-help participation, nonalcoholic beer consumption, and smoking after discharge were assessed by mailed questionnaires. Time to first drink, heavy-drinking lapse, and sustained relapse were analyzed using Kaplan-Meier estimates and multivariate Cox proportional hazards models.

resultsOne-year abstinence was higher among self-help participants (n = 51) than nonparticipants (n = 147) (52.7% vs. 36.8%, p = 0.019) and higher among nonusers (n = 143) than users of nonalcoholic beer (n = 55) (51.2% vs. 15.3%, p < 0.0001). In multivariate models, self-help participation reduced the risk of a drinking lapse (HR 0.51, 95% CI 0.31-0.82) and use of nonalcoholic beer increased the risk (HR 2.30, 95% CI 1.54-3.44). Smoking within one month after discharge, a family history of heavy or problem drinking, and use of psychiatric medication at discharge were also associated with higher hazards. Sensitivity analyses treating dropouts as lapses did not change the results. Heavy-drinking-free rates and sustained-relapse-free rates followed similar patterns. A dose-response pattern emerged: Having all three modifiable protective behaviors (self-help participation, no nonalcoholic beer, and nonsmoking) offered the strongest protection against lapse and relapse [drinking lapse HR 0.18 (95% CI 0.06-0.50); heavy-drinking lapse HR 0.13 (95% CI 0.04-0.48); sustained relapse HR 0.14 (95% CI 0.04-0.48)], two factors showed intermediate protection, and a single factor alone was not significant.

conclusionsStrengthening self-help participation and smoking cessation support at discharge is recommended, and caution is warranted regarding nonalcoholic beer as a potential jeopardy to abstinence.

Indexed as

Alcohol DrinkingAlcoholismBeerSelf-Help GroupsAdultAlcohol AbstinenceEast Asian PeopleFollow-Up StudiesHumansJapanMaleMiddle AgedProspective StudiesRecurrenceSmokingTreatment Outcomealcohol dependencenonalcoholic beerprospective studyself‐help groupsmoking cessation

Identifiers

PMID41620960
PMCPMC12861170

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.