Evidence map›Paper›PMID 41620773›Full record

ReviewEye and vision (London, England)2026

Light and myopia: a focus on the expanding role of non-visual opsins.

Kate Gettinger, Kazuo Tsubota, Kazuno Negishi, Toshihide Kurihara

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Eye and vision (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kate GettingerLaboratory of Photobiology, Keio University School of Medicine, Tokyo, 160-8582, Japan.
Kazuo TsubotaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, 160-8582, Japan.
Kazuno NegishiDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, 160-8582, Japan.
Toshihide KuriharaLaboratory of Photobiology, Keio University School of Medicine, Tokyo, 160-8582, Japan. kurihara.z8@keio.jp.ORCID http://orcid.org/0000-0002-5457-2720

Funding

Japan Agency for Medical Research and Development JP22gm1510007Ministry of Education, Culture, Sports, Science and Technology (MEXT) - Grants-in-Aid for Scientific Research 24K12770
6 · The paper itself

Abstract

Myopia, or near-sightedness, is a growing global concern as its incidence rate continues to dramatically rise. It has been linked to significant ocular morbidity and reduced quality of life. Despite this, much is still largely unknown about the development of and the mechanisms driving the pathogenesis of myopia. As such, myopia prevention and myopia mitigation treatment strategies are occasionally ineffective, can be difficult to adhere to, and have diminishing returns over time. Recently, non-visual opsins (OPN3, OPN4, and OPN5) have emerged as potentially impacting myopia regulation. This narrative review aims to summarize the current understanding of the non-visual opsins and how they might influence myopia. In addition, this review explores how utilizing this knowledge can help develop promising future treatment strategies to reduce the incidence and severity of myopia.

Indexed as

MyopiaMyopia preventionNon-visual opsinsOpsinsUnconventional opsins

Identifiers

PMID41620773
PMCPMC12861076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.