Evidence map›Paper›PMID 41620701›Full record

ArticleBMC pregnancy and childbirth2026

Clinical features of pregnancy-associated aortic dissection and pregnancy outcomes.

Mengge Ke, Jingwen Yu, Li Li, Luyao Qian, Guangming Wang

Abstract read
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Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mengge Ke *Obstetrics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.
Jingwen Yu *Genetic Testing center, The First Affiliated Hospital of Dali University, Dali, 671000, China.
Li LiObstetrics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China.
Luyao QianDepartment of Imaging, Dancheng County People's Hospital, Zhoukou, 477150, China.
Guangming WangGenetic Testing center, The First Affiliated Hospital of Dali University, Dali, 671000, China. wgm1991@dali.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPregnancy complicated by aortic dissection is a rare and severe condition. Due to limited clinical experience, there are currently no standardized management guidelines. Therefore, we summarized and analyzed the clinical data of 33 patients with aortic dissection during pregnancy to gain relevant experience.

methodA total of 33 pregnant women with aortic dissection admitted to the First Affiliated Hospital of Zhengzhou University and the First Affiliated Hospital of Dali University during 13 years from February 1, 2012 to February 28, 2025 were included. The average age was 32.27 years (range: 23–43 years), and the average gestational age at the occurrence of aortic dissection was 31 ± 7 weeks. There were 17 cases (51.5%) of type A aortic dissection (TAAD) and 16 cases (48.5%) of type B aortic dissection (TBAD). Thirteen cases of TAAD (76.5%, 13/17) and ten cases of TBAD (62.5%, 10/16) occurred during late pregnancy or postpartum. Management strategies were based on anatomical type and gestational age (i.e., prioritizing surgery, medical management, or surgery followed by delivery).

resultsAmong the 33 patients, 29 (87.9%) underwent aortic repair surgery, including 14 cases of TAAD (82.4%, 14/17) and 15 cases of TBAD (93.8%, 15/16). A total of 28 patients underwent cesarean section. Among them, 13 cases of TAAD (76.5%, 13/17), 15 cases of TBAD (93.8%). Out of the 33 patients, 6 deaths occurred (18.2%), including 4 TAAD cases with a mortality rate of 23.5% and 2 TBAD cases with a mortality rate of 12.5%. The neonatal mortality rate was 6%, all occurring in TAAD cases.

conclusionFor pregnant women presenting with thoracolumbar pain and a high suspicion of aortic dissection, timely computed tomography angiography (CTA) examination should be performed to avoid missed or delayed diagnosis. Management of aortic dissection during pregnancy should be based on the anatomical type and gestational age to determine the timing of surgery and delivery, which significantly influences maternal and fetal survival rates.

Indexed as

Aortic DissectionPregnancy Complications, CardiovascularPregnancy OutcomeAdultCesarean SectionChinaDissection, Ascending AortaDissection, Thoracic AortaFemaleGestational AgeHumansInfant, NewbornPregnancyRetrospective StudiesYoung AdultAortic dissectionCesarean sectionGestational ageInfant mortality ratePregnancy complications

Identifiers

PMID41620701
PMCPMC12952176

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