ArticleBMC pediatrics2026
Impact of different hemodynamic states of patent ductus arteriosus on cerebral, mesenteric, and renal perfusion in preterm infants: a doppler ultrasound analysis.
Article in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A Comprehensive Review of the Approach to Ultrasonography in Neonatal Shock: The Partnership Between Targeted Neonatal Echocardiography and Point-of-Care Ultrasound.Children (Basel, Switzerland) · 2026Review
- Neonatal acute kidney injury and the patent ductus arteriosus.Pediatric nephrology (Berlin, Germany) · 2026Review
- Cerebral hemodynamic changes in neonates with different types of patent ductus arteriosus: a study using transcranial Doppler ultrasound.BMC pediatrics · 2026Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare end organ hemodynamic in hemodynamically significant (hs) and non-hemodynamically significant (non-hs) patent ductus arteriosus (PDA).
methodsThis retrospective study enrolled preterm infants with PDA who were admitted to the neonatal intensive care unit (NICU) of our center between January 2021 and December 2024. According to comprehensive evaluations of echocardiographic findings and clinical parameters, infants were classified into hemodynamically significant PDA (hsPDA) and non-hsPDA groups. Clinical characteristics and bedside Doppler ultrasound measurements of the anterior cerebral artery (ACA), superior mesenteric artery (SMA), and renal artery (RA) were collected to evaluate the effects of different PDA hemodynamic states on organ blood flow.
resultsA total of 103 preterm infants with PDA were analyzed, including 50 in the hsPDA group and 53 in the non-hsPDA group. There were no significant differences in demographic or clinical variables between the two groups. Compared with the non-hsPDA group, the hsPDA group exhibited lower end-diastolic velocity (EDV) and mean velocity (MV) and higher resistance index (RI) in both the SMA and RA, while parameters of the ACA showed no significant differences. The incidence of necrotizing enterocolitis was higher in the hsPDA group, whereas other complications did not differ significantly between groups.
conclusionsDifferent hemodynamic states of PDA have distinct impacts on organ perfusion in preterm infants. Bedside Doppler ultrasound provides a sensitive tool for early detection of these hemodynamic alterations.
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