Evidence map›Paper›PMID 41620563›Full record

ReviewNPJ digital medicine2026

Flight rules for clinical AI: lessons from aviation for human-AI collaboration in medicine.

Ariel Yuhan Ong, David A Merle, Andreas Pollreisz, Siegfried K Wagner, Mertcan Sevgi, Pearse A Keane, Roman Huemer, Julian Oehling, Markus Jäger, Josef Huemer

Abstract readReview
In one paragraph

Review in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ariel Yuhan OngNIHR Moorfields Biomedical Research Centre, London, UK. ariel.ong@nhs.net.
David A MerleNIHR Moorfields Biomedical Research Centre, London, UK.
Andreas PollreiszDepartment of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
Siegfried K WagnerNIHR Moorfields Biomedical Research Centre, London, UK.
Mertcan SevgiNIHR Moorfields Biomedical Research Centre, London, UK.
Pearse A KeaneNIHR Moorfields Biomedical Research Centre, London, UK.
Roman HuemerFlight Safety Department, Lufthansa German Airlines, Frankfurt, Germany.
Julian OehlingFlight Safety Department, Lufthansa German Airlines, Frankfurt, Germany.
Markus JägerFlight Safety Department, Lufthansa German Airlines, Frankfurt, Germany.
Josef HuemerNIHR Moorfields Biomedical Research Centre, London, UK. josef.huemer1@nhs.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The parallels between medicine and aviation are well-recognised. The aviation industry's early experience with automation improved safety and efficiency, but simultaneously introduced new vulnerabilities and occasionally created misplaced trust in complex systems. Aviation has developed a robust safety framework in response to these costly lessons. In this Perspective, which draws from the experiences of clinicians and aviation experts, we argue that it is now time for the medical community to consider how we can learn from these lessons as artificial intelligence (AI) becomes increasingly integrated into clinical care. We propose that this requires a shift in perspective from AI as "autopilot" to collaboration with a "digital copilot", as well as considerations of practicalities such as scenario-based training, clinician benchmarking, and minimum unaided practice, with the ultimate aim of optimising human-AI collaboration to improve patient care.

Identifiers

PMID41620563
PMCPMC12963479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.