Evidence map›Paper›PMID 41620509›Full record

ArticleNpj mental health research2026

Accelerated recovery using magnesium ibogaine: characterizing the subjective experience of its rapid healing from neuropsychiatric disorders.

Clayton Olash, Derrick Matthew Buchanan, Randi Brown, Afik Faerman, Kirsten Cherian, George Lin, David Spiegel, James J Gross, Nolan Williams

Abstract read
In one paragraph

Article in Npj mental health research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Clayton OlashStanford Brain Stimulation Lab. Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA. claytonolash@gmail.com.
Derrick Matthew BuchananStanford Brain Stimulation Lab. Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA.
Randi BrownStanford Brain Stimulation Lab. Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA.
Afik FaermanStanford Brain Stimulation Lab. Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA.
Kirsten CherianStanford Brain Stimulation Lab. Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA.
George LinDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA.
David SpiegelDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA.
James J Gross *Stanford Psychophysiology Laboratory. Department of Psychology, Stanford University, Palo Alto, CA, USA.
Nolan Williams *Stanford Brain Stimulation Lab. Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnesium-ibogaine, a formulation combining ibogaine with pre- and post-treatment magnesium, was recently found to yield rapid clinical improvements in U.S. Special Operations veterans with TBI and PTSD. Yet, its therapeutic phenomenology during such healing is unknown. We analyzed post-session narratives from 30 male veterans who, after a single open-label magnesium-ibogaine treatment, answered three open-ended questions. A constructivist grounded-theory approach identified four recurrent experiential domains: dialogic trauma re-appraisal marked by guided replay of autobiographical memories; altered-self and mystical connectedness; emotional resolution with surges of forgiveness, love, and renewed purpose; and embodied healing, a vivid sense of neural repair accompanied by cognitive clarity and somatic relief. Together, these themes portray an accelerated, self-directed psychotherapeutic process that dovetails with previously reported improvements in this same cohort, suggesting mind-body mechanisms involving rapid neuroplastic change and highlighting its potential to inform novel approaches to trauma and TBI.

Identifiers

PMID41620509
PMCPMC12860795

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.