Evidence map›Paper›PMID 41620491›Full record

ArticleScientific reports2026

Near-source wastewater surveillance as a non-invasive tool for disease detection in prisons.

O O'Mara, F Hassard, K Jobling, M Quintela-Baluja, S McIntyre-Nolan, L Lundy, A C Singer, S Rahimzadeh, I Stanton, V Castro-Gutierrez and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

O O'MaraUniversity of Essex, Colchester, UK. o.omara@essex.ac.uk.
F HassardCranfield University, Cranfield, UK.
K JoblingNewcastle University, Newcastle upon Tyne, UK.
M Quintela-BalujaDurham University, Durham, UK.
S McIntyre-NolanDurham University, Durham, UK.
L LundyMiddlesex University, London, UK.
A C SingerUK Centre for Ecology and Hydrology, Wallingford, UK.
S RahimzadehUniversity of Essex, Colchester, UK.
I StantonUK Centre for Ecology and Hydrology, Wallingford, UK.
V Castro-GutierrezEnvironmental Pollution Research Center (CICA), University of Costa Rica, San Pedro, Costa Rica.
H Charlotte-SmithCranfield Water Science Institute, Cranfield University, Cranfield, UK.
M VuMiddlesex University, London, UK.
R PedleyNewcastle University, Newcastle upon Tyne, UK.
P AdamouNewcastle University, Newcastle upon Tyne, UK.
D W GrahamNewcastle University, Newcastle upon Tyne, UK.
M Di CesareUniversity of Essex, Colchester, UK. m.dicesare@essex.ac.uk.

Funding

UK Department of Health & Social Care Grant Reference 2020_086UK EPSRC Impact Acceleration Award EP/R511584/1UK NERC award NE/V004883/1
6 · The paper itself

Abstract

Near-source wastewater-based epidemiology (WBE) offers a non-intrusive alternative to clinical testing of whole prison populations. Prisons sit at the centre of high transmission risk but experience limited health-care access and barriers to testing individual prisoners. However, the use of WBE for health protection in prison settings has been limited. To assess its merit during the COVID-19 pandemic, SARS-CoV-2 RNA concentrations were quantified in 680 composite wastewater samples collected from 14 prisons across England and Wales between January and June 2021. Viral RNA was detected in 48% of samples, and wastewater viral loads were found to closely mirror clinical case numbers Lead-lag analysis with adjacent municipal wastewater samples indicated a bidirectional flow between the prisons and their local community: seven prisons exhibited wastewater peaks ahead of their communities, while six lagged, highlighting heterogeneous epidemiological coupling. Marked differences between prisons were apparent in both physicochemical wastewater traits and clinical testing uptake, indicating each institution constitutes a distinct surveillance unit. Collectively, findings here indicate near-source WBE as a rapid, unbiased and scalable tool for disease outbreak detection and for mapping disease flow between prisons and their surrounding communities, advocating its integration into routine health-security frameworks for custodial and other high-density settings.

Indexed as

COVID-19PrisonsSARS-CoV-2WastewaterWastewater-Based Epidemiological MonitoringEnglandHumansRNA, ViralWalesRNA, ViralWastewater

Identifiers

PMID41620491
PMCPMC12917126

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.