Evidence map›Paper›PMID 41619932›Full record

ReviewChest2026

Updates on Rhabdomyolysis: A Clinically Oriented Narrative Review.

Quinlan Richert, Nicholas Miller, Shane Cameron, Bryce Barr, Joel Nkosi, Aditya Sharma

Abstract readReview
In one paragraph

Review in Chest, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Quinlan RichertSection of General Internal Medicine, Department of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada; Section of Critical Care, Department of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada. Electronic address: Quinlan.Richert@umanitoba.ca.
Nicholas MillerSection of Physical Medicine and Rehabilitation, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Shane CameronSection of Rheumatology, Department of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Bryce BarrSection of Nephrology, Department of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Joel NkosiSection of General Internal Medicine, Department of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Aditya SharmaSection of General Internal Medicine, Department of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

topic importanceRhabdomyolysis is the clinical syndrome resulting from the release of skeletal muscle cellular contents into the bloodstream, typically manifesting as limb weakness, myalgias, swelling, myoglobinuria, electrolyte abnormalities, and, critically, acute kidney injury (AKI). Recognition of this complex of clinical and biochemical features is necessary for accurate diagnosis and subsequent management. REVIEW

findingsA precise consensus definition of rhabdomyolysis remains elusive. The McMahon score has proven useful for identifying patients at the highest risk for serious complications and outcomes. Treatment involves careful electrolyte monitoring, crystalloid resuscitation, and dialysis; hyperosmolar therapy remains controversial. Future research should involve randomized controlled trials delineating the role of hyperosmolar therapies, urine alkalinization, and treatment bundles in patients hospitalized with this clinical syndrome. SUMMARY: The goal of this clinically oriented review was to provide an updated summary of the existing evidence and essential knowledge required for the care for patients admitted to the hospital with rhabdomyolysis, including an examination of the syndrome's epidemiology, pathophysiology, clinical manifestations/approach essentials, and basics of management.

Indexed as

Acute Kidney InjuryRhabdomyolysisCrystalloid SolutionsElectrolytesFluid TherapyHumansIncidenceMuscle, SkeletalRenal DialysisCrystalloid SolutionsElectrolytescreatinine kinasemyoglobinrhabdomyolysistrauma

Identifiers

PMID41619932
PMCPMC13494421

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.