Evidence map›Paper›PMID 41619285›Full record

ArticleMedical physics2026

Look-up table correction for beam hardening-induced signal of clinical dark-field chest radiographs.

Maximilian E Lochschmidt, Theresa Urban, Lennard Kaster, Rafael C Schick, Thomas Koehler, Daniela Pfeiffer, Franz Pfeiffer

Abstract read
In one paragraph

Article in Medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maximilian E LochschmidtChair of Biomedical Physics, Department of Physics, TUM School of Natural Sciences, Technical University of Munich, Garching, Germany.ORCID https://orcid.org/0000-0002-5603-0001
Theresa UrbanChair of Biomedical Physics, Department of Physics, TUM School of Natural Sciences, Technical University of Munich, Garching, Germany.ORCID https://orcid.org/0000-0002-0352-8180
Lennard KasterChair of Biomedical Physics, Department of Physics, TUM School of Natural Sciences, Technical University of Munich, Garching, Germany.ORCID https://orcid.org/0009-0002-7355-6328
Rafael C SchickChair of Biomedical Physics, Department of Physics, TUM School of Natural Sciences, Technical University of Munich, Garching, Germany.ORCID https://orcid.org/0000-0001-7650-7009
Thomas KoehlerTUM Institute for Advanced Study, Technical University of Munich, Garching, Germany.ORCID https://orcid.org/0000-0002-1986-0057
Daniela PfeifferInstitute for Diagnostic and Interventional Radiology, School of Medicine and Health, TUM Klinikum, Technical University of Munich (TUM), München, Germany.ORCID https://orcid.org/0000-0003-2002-8337
Franz PfeifferChair of Biomedical Physics, Department of Physics, TUM School of Natural Sciences, Technical University of Munich, Garching, Germany.ORCID https://orcid.org/0000-0001-6665-4363

Funding

Center for Advanced Laser Applications (CALA)European Research Council (ERC Synergy Grant SmartX) SyG101167328Technical University of Munich - Institute for Advanced StudyThe Free State of Bavaria under the Excellence Strategy of the Federal Government and the Länder
6 · The paper itself

Abstract

backgroundThe microstructure of material at a PURPOSE: The objective of this study is to develop a fast, simple, and robust method to correct dark-field signals and bony structures present due to beam hardening on dark-field chest radiographs of study participants.

methodsThe method is based on calibration measurements and image processing. BH by bones and soft tissue is modeled by aluminum and water, respectively, which have no microstructure and thus only generate an artificial dark-field signal. Look-up tables were then created for both. By using a weighted mean of these, forming a single LUT, and using the attenuation images, the artificial dark-field signal and thus the bone structures present are reduced for study participants.

resultsIt was found that applying a correction using a weighted LUT leads to a significant reduction of bone structures in the dark-field image. The weighting of the aluminum component has a substantial impact on the degree to which bone structures remain visible in the dark-field image. Furthermore, a large negative bias in the dark-field image-dependent on the aluminum weighting-was successfully corrected.

conclusionsBH-induced signal in the dark-field images was successfully reduced using the method described. The choice of aluminum weighting to suppress rib structures, as well as the selection of bias correction, should be evaluated based on the specific clinical question.

Indexed as

Image Processing, Computer-AssistedRadiography, ThoracicCalibrationHumansScattering, Small Anglechest radiographydark‐field imaginggrating based imagingmedical imagingmedical physicsx‐ray imaging

Identifiers

PMID41619285
PMCPMC12860541

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.