ReviewHealth economics review2026
A systematic review on indirect costs related to loss of productivity after stroke.
Review in Health economics review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- The Citrus Flavonoid Naringin Confers Neuroprotection Against Cerebral Ischemia by Enhancing Endogenous Antioxidant Capacity and Suppressing Neuroinflammation.Foods (Basel, Switzerland) · 2026Article
- Estimating the indirect economic burden of elevated lipoprotein(a): A 5-year simulation of cardiovascular events and associated patient and caregiver costs.American journal of preventive cardiology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveStroke is a leading cause of death and disability worldwide. The age of stroke cases is decreasing, resulting in a loss of productivity for patients and their informal caregivers. However, socioeconomic impact analyses of stroke often underestimate the importance of these indirect costs. The objective was to conduct a systematic review of indirect costs associated with lost productivity after stroke to highlight their relevance.
methodsA systematic review and meta-analysis were conducted according to PRISMA guidelines. PubMed, Scopus, and Web of Science were searched for scientific publications analyzing loss of work productivity during first post-stroke year. To perform the comparative analysis, the type of stroke was taken into account in relation to the type of productivity loss and the age of the patients. The risk of bias was assessed with Consolidated Health Economic Evaluation Reporting Standards (CHEERS).
resultsA total of 928 records were identified, of which 24 were included in this review. Lost productivity of patient during the first year after stroke onset had a mean value of $6057.98, representing 35.1% of total cost during this period. Patient´s lost productivity was higher in hemorrhagic stroke compared to ischemic stroke ($12,783.17 vs. $8,239.34). In contrast, lost productivity of informal caregivers was slightly higher in ischemic stroke than in hemorrhagic stroke ($5,628.26 vs. $4,205.25). Patients aged 18–44 years had the highest work productivity loss ($16,114.33).
conclusionsIndirect costs represent a significant part of the economic burden of stroke and should therefore be included in future socioeconomic impact studies.
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