ArticleNeurosurgical review2026
Analysis of radiological markers in normal pressure hydrocephalus and their association with postoperative outcomes following shunt procedures.
Article in Neurosurgical review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Differential diagnosis of non-hydrocephalus ventricular dilation and hydrocephalus.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several radiological signs have been recognized as valuable adjuncts to clinical criteria in the diagnosis of normal pressure hydrocephalus (NPH). Certain magnetic resonance imaging (MRI) findings may also provide information on postoperative outcomes following ventricular shunting. However, the evidence remains inconclusive. We conducted a retrospective cohort study including patients from our institution's Clinical Care Center for NPH. Preoperative MRI findings-specifically Evan's Index (EI), callosal angle (CA), disproportionately enlarged subarachnoid space hydrocephalus (DESH), and periventricular white matter hyperintensities (PWMH)-were analyzed in relation to pre- and postoperative clinical status. The median age was 80 years (IQR 75-85), and 68.3% of patients were males. All patients exhibited gait disturbances, 93.3% cognitive impairment, and 83.3% urinary symptoms. Median EI was 0.35 (IQR 0.33-0.37) and median CA was 85.2° (IQR 80-90). DESH was present in 60% of patients, while PWMH were detected in 48.3%. At 1-month follow-up, gait improvement was observed in 66.6%, urinary improvement in 75.6%, and cognitive improvement in 83.0%; sustained at 12 months in 63.8%, 63.8%, and 69.0%, respectively. PWMH correlated with gait improvement (p = 0.04), and DESH with cognitive improvement at 12 months (p = 0.02). DESH and PWMH demonstrated domain-specific prognostic value in idiopathic NPH, whereas EI and CA showed limited predictive utility. Imaging parameters should be interpreted in conjunction with clinical evaluation for outcome prediction.
Indexed as
Identifiers
41619082What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.