A dual-OECT array sensor for discriminating and detecting fluoroquinolone antibiotics using simplified electrode modification.

Yong Xia, Qi Wang, Xu Wang, Liancong Shan, Bo Zhang, Sheng Li, Chang Guo

Abstract read

In one paragraph

Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yong XiaSchool of Mechanical Engineering and Rail Transit, Changzhou University, Changzhou, 213164, China.

Qi WangSchool of Mechanical Engineering and Rail Transit, Changzhou University, Changzhou, 213164, China. wangqi0309@126.com.

Xu WangSchool of Mechanical Engineering and Rail Transit, Changzhou University, Changzhou, 213164, China.

Liancong ShanSchool of Mechanical Engineering and Rail Transit, Changzhou University, Changzhou, 213164, China.

Bo ZhangSchool of Mechanical Engineering and Rail Transit, Changzhou University, Changzhou, 213164, China.

Sheng LiWang Zheng School of Microelectronics, Changzhou University, Changzhou, 213164, China. sli@cczu.edu.cn.

Chang GuoSchool of Mechanical Engineering and Rail Transit, Changzhou University, Changzhou, 213164, China. cguo@cczu.edu.cn.

Funding

Basic Research Program of Jiangsu Province BK20200984Basic Research Program of Jiangsu Province BK20230629National Natural Science Foundation of China 62504023

6 · The paper itself

Abstract

The accurate and rapid detection of fluoroquinolone antibiotics (FQs) is crucial, yet their structural homology often leads to cross-reactivity that compromise accuracy. Herein, we designed a poly(3,4-ethylenedioxythiophene) doped with a poly(styrenesulfonate) (PEDOT:PSS)-based dual-channel organic electrochemical transistor (OECT) array on a flexible, low-cost polyimide substrate. By leveraging the synergistic catalysis of single-walled carbon nanotubes (SWCNTs) and gold nanoparticles (AuNPs), effective discrimination of three FQs was achieved using gate electrodes modified with only two Nafion/SWCNTs/AuNPs composites, differing solely in AuNP mass fraction-this significantly simplifies fabrication for an electronic tongue system (ETS). Aided by principal component analysis (PCA), the system discriminates and quantifies ofloxacin (OFL), levofloxacin (LEV), and ciprofloxacin (CIP) across a wide concentration range of 0.4-1000 μM, with limits of detection (LODs) of 0.32-0.40 μM, while exhibiting excellent selectivity, anti-interference, consistency, stability, and rapid response. The comprehensive performance of this platform establishes a practical foundation for portable FQ sensing in environmental and clinical applications.

Indexed as

Anti-Bacterial AgentsElectrochemical TechniquesFluoroquinolonesBridged Bicyclo Compounds, HeterocyclicElectrodesGoldLimit of DetectionMetal NanoparticlesNanotubes, CarbonPolymersPolystyrenesPrincipal Component AnalysisAnti-Bacterial AgentsBridged Bicyclo Compounds, HeterocyclicFluoroquinolonesGoldNanotubes, Carbonpoly(3,4-ethylene dioxythiophene)PolymersPolystyrenesCarbon nanotubesFluoroquinolonesGold nanoparticlesOrganic electrochemical transistorsPrincipal component analysis

Identifiers

PMID41619036

DOI10.13227/j.hjkx.202110097

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.