Evidence map›Paper›PMID 41618861›Full record

ReviewFEMS microbiology letters2026

C-Type lectin receptors as key modulators of intestinal inflammation: insights into IBD pathogenesis and therapy.

Yinghua Du, Wengang Song, Huixin Peng

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in FEMS microbiology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yinghua DuShandong Provincial Lab for Clinical Immunology Translational Medicine in Universities, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong 250014, P.R. China.
Wengang SongShandong Provincial Lab for Clinical Immunology Translational Medicine in Universities, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong 250014, P.R. China.
Huixin PengShandong Provincial Lab for Clinical Immunology Translational Medicine in Universities, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong 250014, P.R. China.ORCID 0009-0008-3623-2459

Funding

National Natural Science Foundation of China 82271803National Natural Science Foundation of ShanDong Province ZR2024QH157
6 · The paper itself

Abstract

This review focuses on the role of C-type lectin receptors (CLRs) in inflammatory bowel disease (IBD). It outlines their classification, structural features, and functional mechanisms within intestinal immunity. The article comprehensively examines recent advances in understanding the contributions of specific CLRs-including Dectin-1, Mincle, Dectin-3, and the mannose receptor (MR/CD206)-to IBD pathogenesis, particularly their functions in microbial recognition, immune cell activation, and the regulation of inflammatory responses. Finally, the review addresses current research challenges and future directions, with the aim of providing deeper insights into disease mechanisms and facilitating the development of novel CLR-targeted therapies.

Indexed as

Inflammatory Bowel DiseasesLectins, C-TypeAnimalsHumansInflammationInnate Immunity RecognitionLectins, C-TypeC-type lectin receptorDectin-1Dectin-3inflammatory bowel diseasemannose receptorMincle

Identifiers

PMID41618861
PMCPMC13130397

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.