Evidence map›Paper›PMID 41618758›Full record

ReviewThe Journal of international medical research2026

Xeroderma pigmentosum with multiple skin carcinoma and a homogenous

Feng Gao, Ruiye Huang, Yang Lu, Ziyu Guo, Min Li, Weiwei Wu, Wen Li

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Feng GaoDepartment of Plastic and Dermatological Surgery, Affiliated Dermatology Hospital of Hainan Medical University, China.
Ruiye HuangDepartment of Plastic and Dermatological Surgery, Affiliated Dermatology Hospital of Hainan Medical University, China.
Yang LuDepartment of Plastic and Dermatological Surgery, Affiliated Dermatology Hospital of Hainan Medical University, China.
Ziyu GuoDepartment of Plastic and Dermatologic Surgery, the Fifth People's Hospital of Hainan Province, China.
Min LiDepartment of Dermatology, the Fifth People's Hospital of Hainan Province, China.
Weiwei WuDepartment of Plastic and Dermatological Surgery, Affiliated Dermatology Hospital of Hainan Medical University, China.ORCID 0000-0001-5029-6936
Wen LiDepartment of Plastic and Dermatological Surgery, Affiliated Dermatology Hospital of Hainan Medical University, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xeroderma pigmentosum is a rare autosomal recessive genetic disorder characterized by hypersensitivity to ultraviolet radiation and increased risk of skin cancer. Impaired DNA repair mechanisms are considered to be involved in the occurrence and development of this distinct disorder. We present the case of a 48-year-old Chinese woman with facial and chest tumors; these lesions had been rapidly growing over the past 6 months. Pathological biopsy and immunohistology indicated malignant melanoma in facial and chest tumors and squamous cell carcinoma in chest tumors. Using whole-exome sequencing, a site mutation c.2218_2220del (p.Glu)740del in the XPC gene was confirmed. To treat the infection and skin carcinoma, antibiotics and plastic surgery were employed. The identified

Indexed as

Cutaneous Squamous Cell CarcinomaDNA-Binding ProteinsMelanomaNeoplasms, Multiple PrimarySkin NeoplasmsXeroderma PigmentosumBiopsyChinaExome SequencingFemaleHumansMiddle AgedMutationDNA-Binding ProteinsXPC protein, humancase reportmalignant melanomasquamous cell carcinomawhole-exome sequencingXeroderma pigmentosum

Identifiers

PMID41618758
PMCPMC12861359

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.