Evidence map›Paper›PMID 41618614›Full record

ArticleMicrobial biotechnology2026

Exploiting Paraphaeosphaeria minitans and Its Antifungal Metabolites as Bio-Fungicides for Eco-Friendly Management of Head Rot Disease in Cabbage.

Meena V Ruppavalli, Muthusamy Karthikeyan, Iruthayasamy Johnson, Sivaji Jeevanantham, Parthiban V Kumaresan, Balakrishnan Prithiviraj, Sambasivam Periyannan

Abstract read
In one paragraph

Article in Microbial biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meena V RuppavalliDepartment of Plant Pathology, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, India.
Muthusamy KarthikeyanDepartment of Plant Pathology, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, India.
Iruthayasamy JohnsonDepartment of Plant Pathology, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, India.
Sivaji JeevananthamDepartment of Plant Pathology, Annamalai University, Chidambaram, Tamil Nadu, India.
Parthiban V KumaresanDepartment of Plant Pathology, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, India.
Balakrishnan PrithivirajDepartment of Plant, Food and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, Nova Scotia, Canada.
Sambasivam PeriyannanCentre for Crop Health, University of Southern Queensland, Toowoomba, Queensland, Australia.

Funding

MITACS-SICI Partnership IT23781
6 · The paper itself

Abstract

Cabbage head rot, caused by Sclerotinia sclerotiorum, threatens crop yield and quality. Among the 21 mycoparasitic fungi isolated from sclerotia, dormant structure and primary sources of inoculum for the pathogen, the strongest antagonism (78.51% mycelial growth inhibition) was observed in Paraphaeosphaeria minitans strain TNAU-CM 1. Scanning electron microscopy (SEM) revealed its destructive colonisation, including pycnidia and pycnidiospore formation, with visible shrinkage and deformation of sclerotia. Gas chromatography-mass spectrometry (GC-MS) analysis identified 24 bioactive metabolites at the point of interactions between P. minitans TNAU-CM 1 and S. sclerotiorum TNAU-SS-5 strains in dual-culture assays. Further, crude metabolites from P. minitans TNAU-CM 1 cultures inhibited the pathogen's mycelial growth by 54.4% at 100 ppm. In the molecular docking of 14 key compounds, linoleic acid and butyl octyl phthalate, well-known antifungal compounds, displayed the highest binding affinity of -7.6 and -6.2 kcal/mol, respectively, against Saccharomyces cerevisiae cupin protein (1ZNP) YML079w, a homologue of SsYCP1, a YML079-like cupin protein (YCP) and a virulence molecule from S. sclerotiorum. Field trials demonstrated that foliar application of P. minitans TNAU-CM 1 stock solution (8-10 × 10

Indexed as

Antifungal AgentsAscomycotaBrassicaFungicides, IndustrialPlant DiseasesAntibiosisGas Chromatography-Mass SpectrometryMicroscopy, Electron, ScanningMolecular Docking SimulationMyceliumAntifungal AgentsFungicides, Industrialfield trialmolecular dockingmolecular simulationmycoparasitismParaphaeosphaeria minitansSclerotinia sclerotiorum

Identifiers

PMID41618614
PMCPMC12859388

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.