Evidence map›Paper›PMID 41618316›Full record

ArticleSubstance abuse treatment, prevention, and policy2026

Defining exposure for estimating the global burden of alcohol consumption: plausibility testing of WHO methodology using ASEAN countries as a case study.

Jürgen Rehm, Gianna Gayle H Amul, Sawitri Assanangkornchai, Surasak Chaiyasong, Daniela Correia, Noran N Hairi, Enjeline Hanafi, Ahmed S Hassan, Kyaw Ko Ko Htet, Wah Yun Low and 12 more

Abstract read
In one paragraph

Article in Substance abuse treatment, prevention, and policy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Jürgen RehmInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health (CAMH), 250 College Street, Toronto, M5T 1R8, Ontario, Canada. jtrehm@gmail.com.ORCID http://orcid.org/0000-0001-5665-0385
Gianna Gayle H AmulAteneo School of Government, University Katipunan Avenue, Pacifico Ortiz Hall, Fr. Arrupe Road, Social Development Complex, Ateneo de Manila, Quezon City, Loyola Heights, 1108, Philippines.ORCID http://orcid.org/0000-0002-4197-9601
Sawitri AssanangkornchaiCentre for Alcohol Studies, Prince of Songkla University, 15 Kanjanavanich Rd, Hat Yai, Songkhla, 90110, Thailand.ORCID http://orcid.org/0000-0003-2174-3287
Surasak ChaiyasongSocial Pharmacy & Alcohol and Health Promotion Policy Research Units, Faculty of Pharmacy, Mahasarakham University, Maha Sarakham, 44150, Thailand.ORCID http://orcid.org/0000-0001-5863-9382
Daniela CorreiaWHO Regional Office for Europe, UN City, Marmorvej 51, Copenhagen, 2100, Denmark.ORCID http://orcid.org/0000-0001-8886-3211
Noran N HairiDepartment of Social and Preventive Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, 50603, Malaysia.ORCID http://orcid.org/0000-0002-2692-9016
Enjeline HanafiDepartment of Psychiatry, Faculty of Medicine, Universitas Indonesia - dr. Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia.ORCID http://orcid.org/0000-0003-1668-3347
Ahmed S HassanInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health (CAMH), 250 College Street, Toronto, M5T 1R8, Ontario, Canada.ORCID http://orcid.org/0000-0001-8878-5567
Kyaw Ko Ko HtetCentre for Alcohol Studies, Prince of Songkla University, 15 Kanjanavanich Rd, Hat Yai, Songkhla, 90110, Thailand.ORCID http://orcid.org/0000-0001-7853-7308
Wah Yun LowDepartment of Social and Preventive Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, 50603, Malaysia.ORCID http://orcid.org/0000-0003-4409-1509
John Robert C MedinaInstitute of Clinical Epidemiology, National Institutes of Health, University of the Philippines Manila, 623 Pedro Gil St, Ermita, Manila, 1000, Philippines.ORCID http://orcid.org/0000-0001-6647-5453
Jiraluck NontarakDepartment of Epidemiology, Faculty of Public Health, Mahidol University, 420/1 Rajvithi road, Rajthevee, Bangkok, 10400, Thailand.ORCID http://orcid.org/0000-0002-6737-0829
Sok King OngPAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Jalan Tungku Link, Gadong, Darussalam, BE1410, Brunei.ORCID http://orcid.org/0000-0001-8176-8561
Pol RoviraProgram on Substance Abuse & WHO European Region Collaborating Centre at Public Health Agency of Catalonia, Aragó Street 330, Barcelona, Catalonia, 08009, Spain.ORCID http://orcid.org/0000-0002-5444-1560
Kristiana SisteDepartment of Psychiatry, Faculty of Medicine, Universitas Indonesia - dr. Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia.ORCID http://orcid.org/0000-0001-7435-6243
Bundit SornpaisarnInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health (CAMH), 250 College Street, Toronto, M5T 1R8, Ontario, Canada.ORCID http://orcid.org/0000-0001-8541-1172
Vanphanom SychareunFaculty of Public Health, University of Health Sciences, Vientiane, Lao PDR.ORCID http://orcid.org/0000-0002-4313-7336
Wen Ting TongDepartment of Primary Care Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, 50603, Wilayah Persekutuan Kuala Lumpur, Malaysia.ORCID http://orcid.org/0000-0002-9081-191X
Polathep VichitkunakornCentre for Alcohol Studies, Prince of Songkla University, 15 Kanjanavanich Rd, Hat Yai, Songkhla, 90110, Thailand.ORCID http://orcid.org/0000-0003-2309-5308
Siyan YiSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 117549, Singapore.ORCID http://orcid.org/0000-0002-3045-5386
Nyi Nyi ZayarCentre for Alcohol Studies, Prince of Songkla University, 15 Kanjanavanich Rd, Hat Yai, Songkhla, 90110, Thailand.ORCID http://orcid.org/0000-0002-0174-6950
Kevin ShieldInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health (CAMH), 250 College Street, Toronto, M5T 1R8, Ontario, Canada.ORCID http://orcid.org/0000-0003-1871-8849

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComparative risk assessments (CRAs) provide important information for shaping alcohol control policies. Underlying their CRAs, the WHO uses a standardised methodology to assess and detail the levels of alcohol use for all countries and for various regions. This publication uses a case study approach on the member states of the Association of South East Asian Nations (ASEAN) to examine potential biases resulting from the methodology employed by the WHO in calculating exposure values for their CRAs.

methodsResearchers from each of the 10 ASEAN member states identified large population surveys to improve upon the data collected by the WHO monitoring systems to estimate exposure between 2000 and 2022. From these surveys and aggregate data, key indicators were created for each Member State using WHO standardised methodology. Steps were defined to test for implausible values, particularly for the indicator for average level of alcohol consumption among drinkers. Sensitivity analyses were undertaken to identify possible causes of these values. Finally, we compared the results of the implausibility checks with two other regions, the European Union (EU) and the East African Community (EAC), based on data collected by the WHO.

resultsThe indicator for average volume of alcohol consumption among drinkers showed implausibly high values for three ASEAN countries, Lao PDR, Thailand and Viet Nam. Further simulations based on assumptions regarding the prevalence of people with heavy or very heavy drinking levels further corroborated a likely bias. An examination of the constituents of the indicator revealed that the bias for Thailand could be due to responses received to survey questions regarding alcohol abstention, in which a high number of respondents claimed no consumption of alcohol over the past year. For the Lao PDR and Viet Nam, the same problem with survey respondent self-reports on alcohol consumption may exist, but we cannot exclude the possibility that answers to the survey question regarding unrecorded alcohol may also have contributed. Investigations of two further regions of the world also showed some implausible values, albeit to a smaller degree for the EU.

conclusionsPlausibility testing of key monitoring indicators is important and yields important information for improving future monitoring efforts.

Indexed as

AbstentionAlcohoAlcohol per capita consumptionASEANHeavy episodic drinkingMonitoringPopulationRisk factor

Identifiers

PMID41618316
PMCPMC12934120

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.