ArticleBMC plant biology2026
Integrating Meta-QTL mapping and RNA-seq analysis identifies candidate genes for cold tolerance at rice seedling stage.
Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Cold stress severely limits rice growth and yield. To overcome the limitations of traditional QTL mapping, this study employed an integrated Meta-QTL and RNA-seq approach to systematically identify cold tolerance genes in rice seedlings. We meta-analyzed 553 QTLs from 28 published studies (2005-2023), yielding 41 robust meta-QTLs with an average confidence interval of 2.08 Mb across all 12 chromosomes. Parallel transcriptome analysis of seedlings under cold stress identified 14,692 differentially expressed genes (DEGs). Integrative analysis pinpointed 34 high-confidence candidate genes within the meta-QTL intervals, including known 13 stress-responsive genes and 21 previously uncharacterized loci. qRT-PCR validated their dynamic expression under cold stress. This work provides precise genetic targets and a validated framework for breeding cold-tolerant rice, enhancing our understanding of the genetic architecture underlying cold adaptation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.