Evidence map›Paper›PMID 41618166›Full record

ArticleBMC gastroenterology2026

Evaluation of efficacy of a polyglycolic acid sheet in laparoscopic gastrectomy for gastric cancer: a single-center retrospective study.

Senichiro Yanagawa, Yuji Yamamoto, Tetsushi Nakagawa, Mizuki Yamaguchi, Shohei Shiozaki, Kazuaki Tanabe, Masahiro Nakahara, Toshio Noriyuki

Abstract readEvaluation Study
In one paragraph

Article in BMC gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Senichiro YanagawaDepartment of Surgery, JA Onomichi General Hospital, Hiroshima, Japan.
Yuji YamamotoDepartment of Surgery, Hiroshima City North Medical Center Asa Citizens Hospital, 1-2-1 Kameyama Minami, Asakita-Ku, Hiroshima-Shi, Hiroshima, 731-0231, Japan. yuji_yamamoto1020@yahoo.co.jp.
Tetsushi NakagawaDepartment of Surgery, JA Onomichi General Hospital, Hiroshima, Japan.
Mizuki YamaguchiDepartment of Surgery, JA Onomichi General Hospital, Hiroshima, Japan.
Shohei ShiozakiDepartment of Surgery, JA Onomichi General Hospital, Hiroshima, Japan.
Kazuaki TanabeDepartment of Perioperative and Critical Care Management, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Masahiro NakaharaDepartment of Surgery, JA Onomichi General Hospital, Hiroshima, Japan.
Toshio NoriyukiDepartment of Surgery, JA Onomichi General Hospital, Hiroshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric cancer (GC) is one of the most common causes of cancer-related deaths worldwide. Gastrectomy with lymph node dissection is the standard treatment for GC worldwide. Due to advancements in surgical techniques, the use of laparoscopic gastrectomy (LG) has broadened. However, the incidence of post-operative pancreatic fistula (POPF) after LG is higher than that after open surgery, and the definition and measurement of POPF in gastrectomy have not yet been established. We introduced polyglycolic acid (PGA) sheet to prevent POPF after LG and retrospectively evaluated its effectiveness.

methodsBetween April 2022 and June 2024, surgical interventions were performed for 170 patients with GC. Of these patients, 130 underwent LG. Among them, a PGA sheet was used in 62 patients (PGA group), while the remaining 68 patients did not receive PGA sheet (Control group). After propensity score matching, 44 patients were selected for the PGA group and 46 patients for the Control group.

resultsStatistically significant differences in ascitic amylase levels on post-operative day (POD) 1,3 and 5 between the groups were not observed. However, the PGA group showed a significantly greater reduction in the ascitic amylase levels from POD 1 to POD 5 compared with the Control group (p < 0.01). Additionally, no difference was observed in the incidence of Grade IIIa POPF and no POPF greater than Grade IIIb according to the Clavien-Dindo classification.

conclusionsThe use of PGA sheets in LG for GC more pronounced decrease in ascitic amylase levels over time.

Indexed as

GastrectomyLaparoscopyPancreatic FistulaPolyglycolic AcidPostoperative ComplicationsStomach NeoplasmsAgedAmylasesAscitic FluidFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAmylasesPolyglycolic AcidAscitic amylaseGastric cancerLaparoscopic gastrectomyPolyglycolic acidPost-operative pancreatic fistula

Identifiers

PMID41618166
PMCPMC12931015

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.