ArticleNature immunology2026
γδ T cell-derived IL-4 initiates CD8
Abstract read
In one paragraph
Article in Nature immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Innate immune sensing of Plasmodium sporozoite cell traversal drives protective T cell responses.Nature microbiology · 2026Article
- Targeting Golgi-STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant-Associated Infections.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors.
Shirley LeDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0009-0007-8236-2222
Nick DooleyBurnet Institute, Life Science Division, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-9692-5627
Declan MurphyDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.
Shangyi LiuDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.
Luke C GandolfoMelbourne Bioinformatics, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-3599-2455
Zhengyu GeDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-8735-5335
Rose MayDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.
Anton CozijnsenSchool of Biosciences, University of Melbourne, Parkville, Victoria, Australia.
Thomas N BurnDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0003-1763-1418
Charlie JennisonSchool of Biosciences, University of Melbourne, Parkville, Victoria, Australia.
Annabell BachemDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.
Calvin XuDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0003-0753-7639
Hui-Fern KoayDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-3236-9609
Jan SchröderDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.
Damian OyongBurnet Institute, Life Science Division, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-3169-9849
Mayimuna NalubegaBurnet Institute, Life Science Division, Melbourne, Victoria, Australia.
Enny KenangalemMenzies School of Health Research-National Institute of Health Research and Development Malaria Research Program, Timika, Indonesia.
Stephanie GrasInfection and Immunity Program, La Trobe Institute for Molecular Science (LIMS), La Trobe University, Bundoora, Victoria, Australia.ORCID http://orcid.org/0000-0001-7416-038X
Ian A CockburnDivision of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory, Australia.ORCID http://orcid.org/0000-0001-8220-9294
Sammy BedouiDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-7443-0543
Laura K MackayDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-8496-6632
Geoffrey I McFaddenSchool of Biosciences, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-5351-1627
Daniel Fernandez-RuizDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-4040-9121
Michelle BoyleDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-0268-232X
William R HeathDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0001-9670-259X
Lynette BeattieDepartment of Microbiology and Immunology and The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia. lynette.beattie@unimelb.edu.au.ORCID http://orcid.org/0000-0002-5794-7233
Funding
Department of Education and Training | Australian Research Council (ARC) DP220103545Department of Health | National Health and Medical Research Council (NHMRC) 1105817Department of Health | National Health and Medical Research Council (NHMRC) 2002682
Abstract
Dendritic cells (DCs) are pivotal for initiating adaptive immunity, a process triggered by the activation of DCs via pathogen products or damage. Immunization with sporozoites from Plasmodium leads to CD8
Indexed as
CD8-Positive T-LymphocytesDendritic CellsInterleukin-4MalariaReceptors, Antigen, T-Cell, gamma-deltaAnimalsCD40 LigandCD4-Positive T-LymphocytesInterferon-gammaInterleukin-12Lymphocyte ActivationMiceMice, Inbred C57BLMice, KnockoutPlasmodiumCD40 LigandIl4 protein, mouseInterferon-gammaInterleukin-12Interleukin-4Receptors, Antigen, T-Cell, gamma-delta
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.