Evidence map›Paper›PMID 41617926›Full record

ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2026

Fundamentals of healthcare delivery science for the non-health systems scientist: the final step in translational research for late-life psychiatric and neurocognitive disorders.

Christopher C Colenda, Brent P Forester, Rajesh R Tampi, Surafel Tsegaye, Stephen J Bartels

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christopher C ColendaAdjunct Professor, Section Gerontology and Geriatrics, Wake Forest University School of Medicine, Former Chancellor for Health Sciences and President Emeritus of WVU Medicine, West Virginia University, Winston Salem, NC, USA. colendac@gmail.com.ORCID http://orcid.org/0000-0002-1980-9374
Brent P ForesterDr. Frances S. Arkin Chair and Professor of Psychiatry, Tufts University School of Medicine, Boston, MA, USA.
Rajesh R TampiBhatia Family Endowed Chair and Chair of the Department of Psychiatry, Creighton University School of Medicine, Adjunct Professor, Department of Psychiatry, Yale University, Omaha, NE, USA.
Surafel TsegayeResearch Assistant (Volunteer): Tufts University Alzheimer's Research Program and Department of Psychiatry, Tufts University School of Medicine, Boston, MA, USA.ORCID http://orcid.org/0009-0002-2626-4808
Stephen J BartelsDirector, Mongan Institute, James J and Jean H Mongan Professor of Health Policy and Community Health, Professor of Medicine, Massachusetts General Hospital, Boston, MA, USA.

Funding

U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01:AG06110U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01:AG066670
6 · The paper itself

Abstract

This perspective describes why and how Healthcare Delivery Science (HDS) is the stage of translational science research necessary to answer the vexing question of clinical research: "Why is it that what we know works is frustratingly difficult to translate or 'scale' to real-world clinical practice?" Our patients with late-life psychiatric and neurocognitive disorders (PNCDs) are managed in the specialty mental health, general health and long-term care service sectors, and over their lifetimes often require complex, multifaceted and coordinated evidence-based interventions that span all three healthcare sectors to optimize their quality of life and functioning. This perspective defines core principles of HDS and summarizes key implementation and dissemination research methods to further understanding of translational research challenges in real-world settings and to facilitate their widespread dissemination. The importance of Learning Health Systems, especially Age-Friendly Health Systems, as real-world research laboratories, is also reviewed. Importantly, translation of evidence-based interventions across service sectors and large diverse patient populations requires skilled interdisciplinary teams. We characterize existing and projected geriatric professional workforce trends necessary to meet the population health service demands and will offer strategies to ensure success in the growth of the workforce that is required. Selected examples of HDS research are presented that have shown dissemination and translational promise, including a review of the "naturalistic" observational study example associated with private equity investment in the specialty mental health and long-term care service sectors. Finally, HDS's "value proposition" is offered to support the proposition that discovery science priorities could also be shaped from HDS evidence.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.