Evidence map›Paper›PMID 41617707›Full record

ArticleNature communications2026

Insights into the structure and modulation of human TWIK-2.

Qianqian Ma, Ciria C Hernandez, Vikas Navratna, Arvind Kumar, Jaimin K Rana, Jiameng Zong, Abraham Lee, Shyamal Mosalaganti

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Qianqian Ma *Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Ciria C Hernandez *Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Vikas Navratna *Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA. navratna@umich.edu.ORCID 0000-0001-8599-1461
Arvind KumarThermo Fisher Scientific, Waltham, MA, USA.ORCID 0000-0002-8421-8669
Jaimin K RanaLife Sciences Institute, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-0167-7104
Jiameng ZongLife Sciences Institute, University of Michigan, Ann Arbor, MI, USA.ORCID 0009-0004-6322-6565
Abraham LeeDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
Shyamal MosalagantiLife Sciences Institute, University of Michigan, Ann Arbor, MI, USA. mosalaga@umich.edu.ORCID 0000-0002-5934-687X

Funding

Acquisition of Nanion SyncroPatch 384PES10OD025203 · OD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CONE, ROGER D. · 2019 to 2019
$699k
Arnold and Mabel Beckmann FoundationNIH HHS S10 OD025203U.S. Department of Health & Human Services | National Institutes of Health (NIH) DP2150019
6 · The paper itself

Abstract

The Tandem of pore domain in a Weak Inward Rectifying K

Indexed as

Potassium Channels, Tandem Pore DomainCryoelectron MicroscopyHEK293 CellsHumansHydrogen-Ion ConcentrationIon Channel GatingMutagenesis, Site-DirectedPatch-Clamp TechniquesPotassium Channels, Tandem Pore Domain

Identifiers

PMID41617707
PMCPMC12960705

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.