Evidence map›Paper›PMID 41617693›Full record

ArticleNature communications2026

High-throughput methods leveraging robotics and computer vision for the development of therapeutic phage cocktails.

Taylor J R Penke, Aeron Tynes Hammack, Lana J McMillan, Ethan Baker, Pearl Wilcock, Nick Healy, Morgan K Y Wall, Naomi Chavez, Iain Wright, Hannah H Tuson and 8 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Taylor J R PenkeResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US. taylor.penke@locus-bio.com.ORCID 0009-0002-0751-9238
Aeron Tynes HammackResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US. athammack@lbl.gov.ORCID 0000-0002-8966-5978
Lana J McMillanResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Ethan BakerResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Pearl WilcockResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Nick HealyResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Morgan K Y WallResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Naomi ChavezResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Iain WrightResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Hannah H TusonResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.ORCID 0000-0002-7009-882X
Sara WoessnerResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Ashley TramaResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Cameron J PrybolResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.ORCID 0000-0001-7602-9115
Eyra DordiResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Ava GhobadianResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
David G OusteroutResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Nicholas R ConleyResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.
Paul GarofoloResearch and Development, Locus Biosciences, 523 Davis Drive, Morrisville, North Carolina, US.

Funding

U.S. Department of Health & Human Services | Biomedical Advanced Research and Development Authority (BARDA) 75A50120C00169
6 · The paper itself

Abstract

We present the high-throughput automated screening techniques that are being used to develop bacteriophage-based therapeutic products currently under investigation in human clinical trials to combat urinary tract infections

Indexed as

BacteriophagesHigh-Throughput Screening AssaysPhage TherapyRoboticsBacteriaBacterial InfectionsHumans

Identifiers

PMID41617693
PMCPMC12960834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.