Evidence map›Paper›PMID 41617231›Full record

ArticleBMJ open2026

Efficacy of anterior intrusion-based vertical control versus conventional sagittal retraction in adolescents with hyperdivergent mandibular retrognathia: study protocol for a randomised controlled trial.

Shuangshuang Shi, Wei Zhang, Weihua Zhang, Meixiu Lin, Xu Chenyi, Yun Lu, Yuehua Liu

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuangshuang ShiDepartment of Orthodontics, Fudan University Shanghai, Shanghai, China.
Wei ZhangBiomedical Informatics & Statistics Center, School of Public Health, Fudan University, Shanghai, China.
Weihua ZhangDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatolog, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0003-3520-9819
Meixiu LinDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatolog, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-8497-1415
Xu ChenyiDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatolog, Fudan University, Shanghai, China.
Yun LuDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatolog, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0003-1560-0108
Yuehua LiuDepartment of Orthodontics, Shanghai Stomatological Hospital, Shanghai, China liuyuehua@fudan.edu.cn.ORCID http://orcid.org/0000-0003-3033-8873

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHyperdivergent skeletal class II malocclusion in adolescents is characterised by mandibular retrognathia with excessive vertical growth and clockwise mandibular rotation, which can worsen facial profile and airway-related morphology. Although mandibular advancement approaches are commonly used, they may increase the vertical dimension and are suboptimal for patients with long-face patterns. This randomised controlled trial aims to evaluate a micro-implant-assisted protrusion correction technique designed to flatten the occlusal plane and promote counterclockwise mandibular rotation, thereby improving facial profile and pharyngeal space. METHODS AND ANALYSIS: This trial is registered at the Chinese Clinical Trial Registry (ChiCTR; ChiCTR2100054105). This is a two-arm, multicentre, randomised, parallel-controlled trial. Ninety adolescents will be recruited from Shanghai Stomatological Hospital, Zhongshan Hospital (Fudan University), and Xinhua Hospital (Shanghai Jiao Tong University School of Medicine), and will be randomly allocated (1:1) to the test or control group. The control group will receive conventional anterior teeth retraction, whereas the test group will receive a micro-implant-assisted vertical control protocol with occlusal plane flattening. The primary outcome is the change in the A point-nasion-B point angle. Secondary outcomes include changes in the occlusal plane, incisor and molar heights, and facial height. Measurements will be assessed at baseline, at the end of treatment and at 12 months after treatment completion. ETHICS AND DISSEMINATION: This study was approved by the Ethics Committee of the Shanghai Stomatological Hospital (approval no. (2022)006). The results of this study will be made available in peer-reviewed journals. TRIAL REGISTRATION NUMBER: ChiCTR2100054105.

Indexed as

Malocclusion, Angle Class IIRetrognathiaTooth Movement TechniquesAdolescentCephalometryChinaFemaleHumansMaleMandibleMulticenter Studies as TopicRandomized Controlled Trials as TopicTreatment OutcomeVertical DimensionAdolescentsClinical TrialTHERAPEUTICS

Identifiers

PMID41617231
PMCPMC12863360

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.