Evidence map›Paper›PMID 41617213›Full record

ReviewEuropean journal of haematology2026

Retained Central Venous Catheters in Pediatric Patients: Challenges, Mechanisms, and Surgical Strategies-A Narrative Review.

Alice Gismondi, Tommaso Domenico D'Angelo, Chiara Grimaldi, Giorgio Persano, Cristina Martucci, Giovanni Rollo, Giorgia Romano, Gian Luigi Natali, Giulia Cassanelli, Alessandro Crocoli

Abstract readReview
In one paragraph

Review in European journal of haematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alice GismondiSurgical Oncology Unit, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.
Tommaso Domenico D'AngeloSurgical Oncology Unit, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.ORCID https://orcid.org/0009-0006-7999-6227
Chiara GrimaldiSurgical Oncology Unit, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.ORCID https://orcid.org/0000-0003-3551-9286
Giorgio PersanoSurgical Oncology Unit, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.ORCID https://orcid.org/0000-0002-8093-2726
Cristina MartucciSurgical Oncology Unit, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.ORCID https://orcid.org/0000-0002-0037-4534
Giovanni RolloSurgical Oncology Unit, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.ORCID https://orcid.org/0009-0004-7742-8838
Giorgia RomanoSurgical Oncology Unit, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.ORCID https://orcid.org/0009-0009-9197-1761
Gian Luigi NataliInterventional Radiology Unit, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.
Giulia CassanelliInterventional Radiology Unit, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.ORCID https://orcid.org/0000-0003-3162-6690
Alessandro CrocoliSurgical Oncology Unit, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.ORCID https://orcid.org/0000-0003-2157-4233

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-term central venous catheters (CVCs) play a critical role in the management of pediatric patients with chronic illnesses, particularly in oncology. These devices provide reliable vascular access for the administration of chemotherapy, total parenteral nutrition, antibiotics, blood products, and frequent blood sampling.

objectiveReview the etiology, complications, and management of retained long-term central venous catheters in children.

methodsThis review analyzes existing literature and clinical experience to highlight mechanisms of catheter adherence and embolization, with a focus on pediatric-specific challenges.

resultsProlonged catheterization may lead to endothelial injury and fibrotic adherence of the catheter to the vessel wall. Catheter fracture with embolization is a rare but serious complication. Management includes surgical, endovascular, and conservative approaches. Pediatric-specific ethical considerations are vital when fragments are left in situ.

conclusionAwareness of risk factors and timely intervention strategies can mitigate complications from retained CVCs. Further research is needed to understand the long-term effects and improve clinical guidelines.

Indexed as

Catheterization, Central VenousCentral Venous CathetersChildDevice RemovalHumansRisk Factorscatheter embolizationcatheter‐related complicationscatheter retentioncentral venous catheterdevice managementpediatric oncologyretained catheter fragmentsvascular access

Identifiers

PMID41617213
PMCPMC13460488

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.