Evidence map›Paper›PMID 41617190›Full record

Observational studyAmerican journal of perinatology2026

Perinatal and Maternal Outcomes by Indication for Delivery in the Second Trimester.

Kristen A Cagino, Paula L McGee, Maged M Costantine, Michael W Varner, Alan T N Tita, Monica Longo, Barbara J Stoll, John M Thorp, Uma M Reddy, William A Grobman and 7 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in American journal of perinatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Kristen A CaginoDepartment of Obstetrics and Gynecology, University of Texas Health Science Center at Houston, Children's Memorial Hermann Hospital, Houston, Texas, United States.ORCID 0000-0001-8260-434X
Paula L McGeeThe George Washington University Biostatistics Center, Washington, District of Columbia, United States.
Maged M CostantineDepartment of Maternal-Fetal Medicine, The Ohio State University, Columbus, Ohio, United States.ORCID 0000-0003-4076-469X
Michael W VarnerDepartment of Obstetrics and Gynecology, University of Utah Health Sciences Center, Salt Lake City, Utah, United States.ORCID 0000-0001-9455-3973
Alan T N TitaDepartment of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Monica LongoEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, United States.
Barbara J StollEmory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia, United States.
John M ThorpDepartment of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.
Uma M ReddyDepartment of Obstetrics and Gynecology, Columbia University, New York, New York, United States.
William A GrobmanDepartment of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois, United States.
Dwight J RouseDepartment of Obstetrics and Gynecology, Brown University, Providence, Rhode Island, United States.
Hyagriv N SimhanDepartment of Ob/Gyn, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
Jennifer L BailitDepartment of Obstetrics and Gynecology, Case Western Reserve University, Cleveland, Ohio, United States.
Lorraine DugoffDepartment of Maternal-Fetal Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States.
George R SaadeDepartment of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, United States.
Baha M SibaiDepartment of Obstetrics and Gynecology, University of Texas Health Science Center at Houston, Children's Memorial Hermann Hospital, Houston, Texas, United States.
Eunice Kennedy Shriver National Institute of Child Health Human Development Maternal-Fetal Medicine Units Network, Bethesda, Maryland, United States

Funding

SARS-CoV-2 Vaccine Pregnancy RegistryU24HD036801 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI Rebecca Gersnoviez Clifton · 2021 to 2026
$39.2M
Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040485 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Noelia Milena Modad Zork · 2016 to 2026
$3.6M
NICHD Maternal Fetal Medicine Units NetworkUG1HD087192 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Lorraine Dugoff · 2016 to 2026
$3.6M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040544 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI Kelly S Gibson, Angela C. Ranzini · 2016 to 2026
$3.5M
Maternal-Fetal Medicine Units Network -- The Northwestern Study CenterUG1HD040512 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Lynn M Yee · 2016 to 2026
$3.4M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040500 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI DWIGHT J ROUSE · 2016 to 2026
$3.4M
UofU Maternal-Fetal Medicine Units (MFMU) Network: Clinical CentersUG1HD034208 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Torri D Metz · 2016 to 2026
$3.4M
NICHD Maternal Fetal Medicine Units NetworkUG1HD027915 · NICHD · OHIO STATE UNIVERSITY · PI Maged Costantine · 2016 to 2026
$3.3M
UNC MFMU: Advancing Perinatal Health via Definitive, Multi-Site Clinical StudiesUG1HD040560 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI John M Thorp · 2016 to 2026
$3.3M
NICHD Cooperative Multicenter Neonatal Research NetworkUG1HD053109 · NICHD · UNIVERSITY OF IOWA · PI Tarah Trinity Colaizy · 2016 to 2026
$3.2M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD087230 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HYAGRIV N SIMHAN · 2016 to 2026
$3.2M
NICHD Maternal-Fetal Medicine Units (MFMU) NetworkUG1HD040545 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Hector Mendez-Figueroa · 2016 to 2026
$3.2M
Eunice Kennedy Shriver National Institute of Child Health and Human Development U24 HD036801Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD027851Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD027869Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD027915Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD034208Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD040485Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD040500Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD040512Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD040544Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD040545Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD040560Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD053097Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD053109Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD087192Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD087230Eunice Kennedy Shriver National Institute of Child Health and Human Development UG1 HD087230, UG1 HD027869, UG1 HD027915, UG1 HD03NICHD NIH HHS U24 HD036801NICHD NIH HHS UG1 HD027851NICHD NIH HHS UG1 HD027869NICHD NIH HHS UG1 HD027915NICHD NIH HHS UG1 HD034208NICHD NIH HHS UG1 HD040485NICHD NIH HHS UG1 HD040500NICHD NIH HHS UG1 HD040512NICHD NIH HHS UG1 HD040544NICHD NIH HHS UG1 HD040545NICHD NIH HHS UG1 HD040560NICHD NIH HHS UG1 HD053097NICHD NIH HHS UG1 HD053109NICHD NIH HHS UG1 HD087192NICHD NIH HHS UG1 HD087230
6 · The paper itself

Abstract

Objective: Perinatal and maternal morbidity in the setting of preterm birth may differ by delivery indication. We compared perinatal and maternal outcomes of second-trimester (24 Study Design: Secondary analysis of an observational cohort study of singleton and twin preterm deliveries before 35 weeks' gestation at 33 hospitals across the United States. Singletons without congenital anomalies who were delivered due to PE-SF or PPROM from 24 Results: Among the 7,515 in the original cohort, 164 deliveries for PE-SF and 119 deliveries following PPROM were included. Individuals with PE-SF were more likely to have a BMI of ≥30 kg/m Conclusion: Second-trimester preterm birth indicated for PE-SF was associated with a higher rate of fetal death than birth for PPROM. Composite neonatal and maternal morbidity did not differ by indication. Key Points: · Fetal death occurred more frequently in individuals with PE-SF compared with PPROM in the second trimester.. · Composite perinatal and maternal outcomes were similar between groups.. · Our findings can be used for risk stratification and survival prediction rates..

Indexed as

Pre-EclampsiaPregnancy OutcomePregnancy Trimester, SecondPremature BirthPremature Rupture of Fetal MembranesAdultBronchopulmonary DysplasiaCerebral Intraventricular HemorrhageCohort StudiesEnterocolitis, NecrotizingFemaleGestational AgeHumansInfant, NewbornInfant, Small for Gestational AgeLeukomalacia, Periventricular

Identifiers

PMID41617190
PMCPMC13012069

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.