ArticleInfection and immunity2026
The L-lactate dehydrogenase LldD contributes to oxidative stress resistance, survival from neutrophils, and host colonization in
Jerri M Lankford, Willis E Barr, Cole A Andersen, Amitha A Karuppiah, Keena S Thomas, Ian J Glomski, Wen-Chi Huang, Alison K Criss, Aimee D Potter
Abstract read
In one paragraphArticle in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors.
Jerri M LankfordDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.ORCID 0009-0009-8013-3818 Willis E BarrDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Cole A AndersenDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.ORCID 0009-0007-3260-1790 Amitha A KaruppiahDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Keena S ThomasDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA.
Ian J GlomskiDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA.ORCID 0009-0006-3738-3430 Wen-Chi HuangDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Alison K CrissDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0001-7738-3757 Aimee D PotterDepartment of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.ORCID 0000-0003-1473-1149 Funding
INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007496 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Michael G. Brown, Coleen A McNamara · 1995 to 2026
$10.2MNeisseria gonorrhoeae metal transporters that subvert nutritional immunityR01AI127793 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI CYNTHIA N CORNELISSEN, Alison K Criss · 2017 to 2026
$6.8MSurvival of Neisseria gonorrhoeae after primary human neutrophil challengeR01AI097312 · NIAID · UNIVERSITY OF VIRGINIA · PI CRISS, ALISON K · 2012 to 2022
$4.6MSurvival of Neisseria gonorrhoeae after primary human neutrophil challengeR37AI097312 · NIAID · UNIVERSITY OF VIRGINIA · PI Alison K Criss · 2025 to 2026
$1.1MNeisseria gonorrhoeae central metabolism in the context of neutrophilic inflammationR21AI161302 · NIAID · UNIVERSITY OF VIRGINIA · PI CRISS, ALISON K · 2021 to 2022
$444kNIAID NIH HHS R01 AI097312NIAID NIH HHS R01 AI127793NIAID NIH HHS R21 AI161302NIAID NIH HHS R37 AI097312NIAID NIH HHS T32 AI007496NIH HHS R01AI097312, R01AI127793, R21AI161302NIH HHS T32AI007496, R01AI127793-07W2Roy J. and Lucille A. Carver College of Medicine, University of Iowa Start up fundsSchool of Medicine, University of Virginia Harrison Distinguished Teaching Professorship
6 · The paper itselfAbstract
Metabolic adaptation to the host environment is a key determinant of bacterial pathogenesis, enabling both colonization and invasive disease. This is particularly true for
Indexed as
Bacterial ProteinsGonorrheaL-Lactate DehydrogenaseNeisseria gonorrhoeaeNeutrophilsOxidative StressAnimalsHost-Pathogen InteractionsHumansMiceReactive Oxygen SpeciesVirulenceBacterial ProteinsL-Lactate DehydrogenaseReactive Oxygen Speciesbacterial metabolismhost-pathogen interactionslactate dehydrogenaseNeisseria gonorrhoeaeneutrophilsoxidative stress resistance
Identifiers
PMID41616255
PMCPMC12974116
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