Evidence map›Paper›PMID 41616247›Full record

ArticlemSphere2026

Use of a human immortalized microglia cell line to study recognition, phagocytosis, and intracellular survival of

Robbi L Ross, Kassandra Arias-Parbul, Zane M Douglass, Katrina L Adams, Felipe H Santiago-Tirado

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Phagosome maturation during fungal infection.Current opinion in microbiology · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Robbi L RossDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Kassandra Arias-ParbulDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Zane M DouglassDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Katrina L AdamsDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Felipe H Santiago-TiradoDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.ORCID 0000-0002-6453-4904

Funding

Host and fungal factors important for the cryptococcal intracellular nicheR01AI177875 · NIAID · UNIVERSITY OF NOTRE DAME · PI Felipe H Santiago-Tirado · 2023 to 2026
$1.6M
The role of a pleiotropic drug resistance (PDR) transporter in the cryptococcal-host interactionsR21AI171742 · NIAID · UNIVERSITY OF NOTRE DAME · PI SANTIAGO-TIRADO, FELIPE H · 2023 to 2024
$430k
Defining the fungal-host interactions between the pathogenic yeast Cryptococcus neoformans and human microgliaF31AI194736 · NIAID · UNIVERSITY OF NOTRE DAME · PI Robbi Ross · 2025 to 2026
$100k
NIAID NIH HHS F31 AI194736NIAID NIH HHS R01 AI177875NIAID NIH HHS R21 AI171742NIH HHS F31AI194736NIH HHS R01AI177875NIH HHS R21AI171742University of Notre Dame BIPH
6 · The paper itself

Abstract

IMPORTANCE: While

Indexed as

Cryptococcus neoformansMicrobial ViabilityMicrogliaPhagocytosisCell LineHost-Pathogen InteractionsHumansMacrophagesMeningitis, CryptococcalC20 cellscryptococcal meningitisCryptococcus neoformansmicroglia

Identifiers

PMID41616247
PMCPMC12931265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.