Article in Circulation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors.
Khalid Elsaafien *Neuroscience Institute, College of Arts and Sciences (K.E., M.K.K., D.N.J., C.J.V., K.A.S., J.E.S., A.D.d.K., E.G.K.), Georgia State University, Atlanta.ORCID 0000-0001-9581-918X
Matthew K Kirchner *Neuroscience Institute, College of Arts and Sciences (K.E., M.K.K., D.N.J., C.J.V., K.A.S., J.E.S., A.D.d.K., E.G.K.), Georgia State University, Atlanta.ORCID 0000-0001-6960-7685
Caitlin Baumer-HarrisonDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia (C.B.-H.).ORCID 0000-0002-6287-5887
Yalun TanDepartment of Pharmacodynamics (Y.T.), College of Pharmacy, University of Florida, Gainesville.ORCID 0000-0003-0786-7865
Dominique N JohnsonNeuroscience Institute, College of Arts and Sciences (K.E., M.K.K., D.N.J., C.J.V., K.A.S., J.E.S., A.D.d.K., E.G.K.), Georgia State University, Atlanta.
Carly J VincentNeuroscience Institute, College of Arts and Sciences (K.E., M.K.K., D.N.J., C.J.V., K.A.S., J.E.S., A.D.d.K., E.G.K.), Georgia State University, Atlanta.ORCID 0009-0001-1572-8446
Karen A ScottNeuroscience Institute, College of Arts and Sciences (K.E., M.K.K., D.N.J., C.J.V., K.A.S., J.E.S., A.D.d.K., E.G.K.), Georgia State University, Atlanta.ORCID 0000-0002-4133-423X
Jieqiang ZhouDepartments of Pharmaceutics and Pharmacotherapy and Translational Research (J.Z., Y.Z., Y.L., J.B.), College of Pharmacy, University of Florida, Gainesville.
Yongzhen ZhangDepartments of Pharmaceutics and Pharmacotherapy and Translational Research (J.Z., Y.Z., Y.L., J.B.), College of Pharmacy, University of Florida, Gainesville.
Yinzhi LangDepartments of Pharmaceutics and Pharmacotherapy and Translational Research (J.Z., Y.Z., Y.L., J.B.), College of Pharmacy, University of Florida, Gainesville.ORCID 0000-0002-6857-4516
Jürgen BulittaDepartments of Pharmaceutics and Pharmacotherapy and Translational Research (J.Z., Y.Z., Y.L., J.B.), College of Pharmacy, University of Florida, Gainesville.ORCID 0000-0001-7352-3097
Javier E SternNeuroscience Institute, College of Arts and Sciences (K.E., M.K.K., D.N.J., C.J.V., K.A.S., J.E.S., A.D.d.K., E.G.K.), Georgia State University, Atlanta.ORCID 0000-0002-9310-0486
Annette D de KloetNeuroscience Institute, College of Arts and Sciences (K.E., M.K.K., D.N.J., C.J.V., K.A.S., J.E.S., A.D.d.K., E.G.K.), Georgia State University, Atlanta.ORCID 0000-0002-7213-6957
Eric G KrauseNeuroscience Institute, College of Arts and Sciences (K.E., M.K.K., D.N.J., C.J.V., K.A.S., J.E.S., A.D.d.K., E.G.K.), Georgia State University, Atlanta.ORCID 0000-0002-2718-3113
Funding
Interrogating stress-relieving neural circuits to alleviate cardiovascular diseaseR35HL150750 · NHLBI · UNIVERSITY OF FLORIDA · PI Eric Gerald Krause · 2020 to 2026
$5.9M
Calcium-dependent autoregulation of vasopressin neurons in a rodent model of heart failure.R00HL168434 · NHLBI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI Matthew Kirchner · 2025 to 2026
$498k
Investigating Afferent Baroreflex Dysfunction in HypertensionR00HL175100 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI Khalid El Saafien · 2025 to 2026
$480k
Investigating Afferent Baroreflex Dysfunction in HypertensionK99HL175100 · NHLBI · GEORGIA STATE UNIVERSITY · PI EL SAAFIEN, KHALID · 2024 to 2024
backgroundThe paraventricular nucleus of the hypothalamus (PVN) orchestrates neuroendocrine and autonomic output to maintain systolic blood pressure (SBP). Emerging evidence suggests that the PVN utilizes paracrine signals to modulate neighboring neurons. Here, we test the hypothesis that OXT (oxytocin)-synthesizing neurons of the PVN (PVN
methodsTo test the hypothesis, experiments were conducted ex vivo and in vivo in mice with the expression of ChR2 (channelrhodopsin-2) and EYFP (enhanced yellow fluorescent protein) directed to cells synthesizing OXT.
resultsWe found >90% of EYFP-neurons were immunolabeled for OXT, and blue light elicited action potentials in these neurons. This confirmed directed/functional expression of ChR2-EYFP within PVN
conclusionsCollectively, our results reveal that firing of PVN
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Oxytocin and Vasopressin Cross Talk Within the Brain Increases Blood Pressure. · full record | OpenQuestion