Evidence map›Paper›PMID 41615748›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Evolutionary pathways in epistatic mechanical networks.

Samar Alqatari, Sidney R Nagel

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Samar AlqatariDepartment of Physics, The James Franck and Enrico Fermi Institutes, The University of Chicago, Chicago, IL 60637.ORCID 0000-0002-4433-7946
Sidney R NagelDepartment of Physics, The James Franck and Enrico Fermi Institutes, The University of Chicago, Chicago, IL 60637.ORCID 0000-0003-3486-8898

Funding

National Science Foundation (NSF) 2317138U.S. Department of Energy (DOE) DE-SC0020972
6 · The paper itself

Abstract

An elastic spring network is an example of evolvable matter. It can be pruned to couple separated pairs of nodes so that when a strain is applied to one of them, the other responds either in-phase or out-of-phase. This produces two pruned networks, with incompatible functions, that are nearly identical but differ from each other by a set of "mutations" each of which removes or adds a single bond in the network. We generate ensembles of network pairs that differ by a fixed number,

Indexed as

Biological EvolutionEpistasis, GeneticEvolution, MolecularModels, GeneticMutationepistasisevolutionfitness landscapefunction switchmechanical network

Identifiers

PMID41615748
PMCPMC12867688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.