Evidence map›Paper›PMID 41615563›Full record

ReviewBlood research2026

The role of m6A RNA methyltransferase METTL3 in drug resistance mechanisms in acute myeloid leukemia.

Suresh Prajapati, Charmi Jyotishi, Mansi Patel, Reeshu Gupta

Abstract readReview
In one paragraph

Review in Blood research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Suresh PrajapatiParul Institute of Applied Sciences, Parul University, Post Limda, Waghodia Road, Vadodara, Gujarat, 391760, India.
Charmi JyotishiParul Institute of Applied Sciences, Parul University, Post Limda, Waghodia Road, Vadodara, Gujarat, 391760, India.
Mansi PatelResearch and Development Cell, Parul Institute of Applied Sciences, Parul University, Post Limda, Waghodia RoadGujarat, Vadodara, 391760, India.
Reeshu GuptaParul Institute of Applied Sciences, Parul University, Post Limda, Waghodia Road, Vadodara, Gujarat, 391760, India. reeshu.gupta25198@paruluniversity.ac.in.ORCID http://orcid.org/0000-0002-1743-4388

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review examines the role of METTL3, a core RNA methyltransferase, in therapeutic resistance in acute myeloid leukemia (AML) and discusses emerging strategies to address this challenge. METTL3 regulates N

Indexed as

Acute Myeloid LeukemiaDrug resistanceMETTL3PROTACs

Identifiers

PMID41615563
PMCPMC12858683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.