Evidence map›Paper›PMID 41615558›Full record

ArticleCardiovascular intervention and therapeutics2026

Effect of prehospital 12-Lead electrocardiography on the emergent medical system for ST-Segment-Elevation myocardial infarction during the coronavirus disease 2019 (COVID-19) pandemic: results from the K-ACTIVE registry.

Yasuhiro Tanabe, Yoshihiro J Akashi, Atsuo Maeda, Junya Ako, Yuji Ikari, Toshiaki Ebina, Kouichi Tamura, Masayuki Shibata, Kazuki Fukui, Kiyoshi Hibi and 3 more

Abstract readMulticenter Study
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In one paragraph

Article in Cardiovascular intervention and therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yasuhiro TanabeDepartment of Cardiology , St. Marianna University School of Medicine , Kawasaki, Japan. y-tanabe@marianna-u.ac.jp.ORCID http://orcid.org/0000-0001-8580-9404
Yoshihiro J AkashiDepartment of Cardiology , St. Marianna University School of Medicine , Kawasaki, Japan.
Atsuo MaedaDepartment of Emergency and Disaster Medicine , Showa University School of Medicine , Tokyo, Japan.
Junya AkoDivision of Cardiology , Kitasato University School of Medicine , Sagamihara, Japan.
Yuji IkariDivision of Cardiology , Tokai University School of Medicine , Isehara, Japan.
Toshiaki EbinaDepartment of Laboratory Medicine and Clinical Investigation , Yokohama City University Medical Center , Yokohama, Japan.
Kouichi TamuraDepartment of Medical Science and Cardiorenal Medicine , Yokohama City University Graduate School of Medicine , Yokohama, Japan.
Masayuki ShibataDivision of Cardiology , Kanto Rosai Hospital , Kawasaki, Japan.
Kazuki FukuiDivision of Cardiology , Kanagawa Cardiovascular and Respiratory Center , Yokohama, Japan.
Kiyoshi HibiDepartment of Cardiology , Yokohama City University Graduate School of Medicine , Yokohama, Japan.
Ichiro MichishitaDivision of Cardiology , Yokohama Sakae Kyosai Hospital , Yokohama, Japan.
Kazuo KimuraDepartment of Cardiovascular Medicine , Yokosuka City Hospital , Yokosuka, Japan.
Hiroshi SuzukiDivision of Cardiology , Showa University Fujigaoka Hospital , Yokohama, Japan.

Funding

Grant-in-Aid for Scientific Research 20 K08434
6 · The paper itself

Abstract

Prehospital-electrocardiography (ECG) has been shown to be effective in reducing time to reperfusion in patients with myocardial infarction; however, its utility in disaster settings remains unclear.K-ACTIVE is a cardiovascular emergency registry comprising 58 hospitals in Kanagawa, Japan. 5,821 ST-segment–elevation myocardial infarction (STEMI) cases were enrolled during before-pandemic (January 2017 to December 2019; N = 3,946) and pandemic (January 2020 to November 2021; N = 1,875) (Cohort A). Additionally, 2,980 cases with complete time-course documentation from symptom onset to device insertion were analyzed (Cohort B). In Cohort A, the rates of primary percutaneous coronary intervention (PCI) and pre-hospital-ECG use were preserved during pandemic (94.1% vs. 95.4%, P = 0.206; and 47.8% vs. 45.0%, P = 0.054, respectively). In the analysis of Cohort B, all components of the time interval from symptom onset to device insertion were found to be significantly prolonged or showed a trend toward prolongation during pandemic. After propensity score matching based on age, sex, Killip classification, and history of MI, the time from emergency medical service (EMS) arrival to catheter laboratory entry was shorter in patients with prehospital ECG than in those without (62.0 (49.0–87.0) vs. 65.0 (53.0–85.0) minutes, P = 0.045). Moreover, this time interval did not change during pandemic in patients with prehospital-ECG (61.0 (49.0–86.0) vs. 64.0 (49.0–88.5) minutes, P = 0.33), whereas it was prolonged in patients without prehospital-ECG (64.0 (51.0–84.0) vs. 70.5 (57.0–90.0) minutes, P = 0.002)Prehospital-ECG enabled timely transfer to the catheterization laboratory even under disaster conditions.

Indexed as

COVID-19ElectrocardiographyEmergency Medical ServicesPercutaneous Coronary InterventionST Elevation Myocardial InfarctionAgedFemaleHumansJapanMaleMiddle AgedPandemicsRegistriesSARS-CoV-2Time-to-TreatmentAcute coronary syndromeCoronavirus disease 2019 (COVID-19)Emergent medical systemPrehospital electrocardiographyST-segment–elevation myocardial infarction

Identifiers

PMID41615558

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.