Evidence map›Paper›PMID 41615485›Full record

Observational studyWorld journal of urology2026

Membranous urethral length as a predictor for urinary incontinence after holmium enucleation of the prostate for benign prostatic hyperplasia.

Nick Lee, Tarek Benzouak, David-Dan Nguyen, Sébastien Belliveau, Liam Murad, Lynda Kadi, Nathan Perlis, Rodney H Breau, Dean Elterman, Bilal Chughtai and 5 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Nick LeeDivision of Urology, Department of Surgery, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada. nick.lee@umontreal.ca.ORCID http://orcid.org/0000-0002-7166-0503
Tarek BenzouakFaculty of Medicine, McGill University, Montreal, QC, Canada.
David-Dan NguyenDivision of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Sébastien BelliveauDivision of Urology, Department of Surgery, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Liam MuradFaculty of Medicine, McGill University, Montreal, QC, Canada.
Lynda KadiDepartment of Radiology, Université de Montréal, Montréal, QC, Canada.
Nathan PerlisDivision of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Rodney H BreauDivision of Urology, Department of Surgery, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.
Dean EltermanDivision of Urology, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Bilal ChughtaiDepartment of Urology, Northwell Health, Manhasset, NY, USA.
Dan R GralnekDepartment of Urology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Damien OliviéDepartment of Radiology, Université de Montréal, Montréal, QC, Canada.
Malek MeskawiDivision of Urology, Department of Surgery, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Cristina NegreanDivision of Urology, Department of Surgery, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Naeem BhojaniDivision of Urology, Department of Surgery, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHolmium laser enucleation of the prostate (HoLEP) is as an effective, size-independent treatment for benign prostatic hyperplasia (BPH) with durable outcomes. However, one of its adverse outcomes is post-operative stress urinary incontinence (SUI). We sought to determine if membranous urethral length (MUL) as measured on preoperative magnetic resonance imaging is a predictor for post-operative SUI in patients undergoing HoLEP for BPH.

methodsA single-center, retrospective observational study was conducted on 147 consecutive patients who underwent HoLEP for BPH between 2018 and 2024. Preoperative baseline characteristics, perioperative details, and SUI outcomes at 1, 3, and 6 months were collected. Binary logistic regression was used to assess the association between MUL and SUI at each follow-up interval.

resultsMedian MUL was 8.2 mm (IQR 6.1-11.0), and post-operative SUI incidences were 73 (49.7%), 36 (24.5%), and 16 (10.9%) at 1, 3, and 6 months respectively. Longer MUL was significantly associated with lower odds of SUI at 1 month (OR: 0.86, 95% CI: 0.77-0.96, p = 0.009), 3 months (OR: 0.77, 95% CI: 0.65-0.91, p = 0.002), and 6 months (OR: 0.65, 95% CI: 0.49-0.87, p = 0.004). Internal validation demonstrated good discrimination (areas under the curve of 0.73, 0.75, and 0.83 at 1, 3, and 6 months) with well-calibrated models, and decision curve analysis confirmed clinical utility within prespecified risk thresholds.

conclusionsLonger MUL is significantly associated with lower rates of SUI following HoLEP at 1, 3, and 6 months. Longer MUL may serve as a valuable predictive factor for continence recovery and should be considered during preoperative counseling and surgical decision planning.

Indexed as

Lasers, Solid-StateLaser TherapyPostoperative ComplicationsProstatectomyProstatic HyperplasiaUrethraUrinary Incontinence, StressAgedHumansMagnetic Resonance ImagingMaleMiddle AgedPredictive Value of TestsRetrospective StudiesBenign prostatic hyperplasiaHolmium laser enucleation of the prostateMagnetic resonance imagingMembranous urethral lengthProstate volumeUrinary continence

Identifiers

PMID41615485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.