ArticleFish physiology and biochemistry2026
Effects of acute cold stress on the physiological and biochemical dynamics of Nile tilapia (Oreochromis niloticus Linn.): in vivo and in vitro studies.
Article in Fish physiology and biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Acute Thermal Elevation Alters Cellular Metabolic Activity, Redox Balance, and Iron Homeostasis in Butterfly Lizards (Animals : an open access journal from MDPI · 2026Article
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Authors and funding
5 authors.
Funding
Abstract
This study was aimed at examining the physiological and biochemical response of live Nile tilapia (NT) (Oreochromis niloticus Linn.) and Nile tilapia blood cells (NTBC) to abrupt ambient temperature reductions. NT was exposed to water temperatures between 24 °C and 14 °C during the experiment, while NTBC was subjected to temperatures between 24 °C and 12 °C, with a 2 °C temperature reduction at each stage. Physiological parameters of NT were assessed, including core body temperature, heart rate, ventilation rate, body coloration score, and oxygen saturation. In addition, biochemical parameters of NTBC were measured, i.e., total antioxidant capacity, hydrogen peroxide, malondialdehyde, nitric oxide, and mitochondrial activity. It was found that lowering the water temperature from 24 °C to 14 °C caused a drop in core body temperature and ventilation rates (P < 0.05), while heart rates rose at 18 °C (P < 0.05) before falling. Body coloration scores became higher at 20 °C and grew more intense as the water temperature fell further (P < 0.05). Mitochondrial activity peaked at 18 °C (P < 0.05), while malondialdehyde rose significantly between 16 °C and 12 °C (P < 0.05). Total antioxidant capacity decreased at 18 °C (P < 0.05) and remained low to 12 °C. Nitric oxide dropped at 20 °C and 12 °C (P < 0.05), while hydrogen peroxide peaked at 14 °C (P < 0.05). These findings indicate that NT is highly sensitive to temperatures below 20 °C, which increases oxidative stress and requires enhanced antioxidant defenses below 18 °C. Finally, the results align between in vivo and in vitro experiments.
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Registered trials
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