Evidence map›Paper›PMID 41615442›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

The association between scoliosis research society-22r and cosmetic parameters in female patients with adolescent idiopathic scoliosis.

Zhengye Zhao, Aoran Maheshati, Shufang Zhu, Terry Jianguo Zhang, Nan Wu

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Zhengye ZhaoDepartment of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Beijing Key of Big Data Innovation and Application for Skeletal Health Medical Care, Key Laboratory of Big Data for Spinal Deformities, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Aoran MaheshatiDepartment of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Beijing Key of Big Data Innovation and Application for Skeletal Health Medical Care, Key Laboratory of Big Data for Spinal Deformities, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Shufang ZhuSchool of Biomedical Engineering, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Terry Jianguo ZhangDepartment of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Beijing Key of Big Data Innovation and Application for Skeletal Health Medical Care, Key Laboratory of Big Data for Spinal Deformities, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. jgzhang_pumch@yahoo.com.
Nan WuDepartment of Orthopedic Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Beijing Key of Big Data Innovation and Application for Skeletal Health Medical Care, Key Laboratory of Big Data for Spinal Deformities, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. dr.wunan@pumch.cn.

Funding

CAMS Innovation Fund for Medical Sciences 2021-I2M-1-051National High Level Hospital Clinical Research Funding 2022-PUMCH-C-033National High Level Hospital Clinical Research Funding 2022-PUMCH-D-004National Key Research and Development Program of China 2023YFC2507700Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences No. 2019PT320025
6 · The paper itself

Abstract

purposeCompared to linear models, segmented models allow for the identification of threshold effects in severe spinal deformities, beyond which patients' health-related quality of life (QoL) declines significantly. However, no study has established threshold values for cosmetic parameters in adolescent idiopathic scoliosis (AIS). This study aims to determine the threshold values of cosmetic parameters in spinal deformity severity measurements.

methodsA total of 278 female adolescents with idiopathic scoliosis (age: 14.7 ± 2.0; maximum Cobb angle: 49.4° ± 15.9°) completed the SRS-22r questionnaire. The Cobb angle and cosmetic parameters were measured using X-rays and Image-Pro Plus 6.0 software. Segmented and linear regression models were used to evaluate the correlation and explanatory power (R²) between SRS-22r domains and spinal deformity indicators, and to identify the thresholds of cosmetic parameters that significantly impact SRS-22r scores.

resultsLateral shoulder tilt (LST) predicted significantly more variance in all SRS-22r domains using segmented (R

conclusionThis study shows that QoL stays relatively stable until LST exceeds a threshold of 5.2°, after which it drops markedly. Although the link between QoL and cosmetic parameters is weak, segmented models provide a better explanation than linear models.

Indexed as

Quality of LifeScoliosisAdolescentChildFemaleHumansRadiographySeverity of Illness IndexSurveys and QuestionnairesAdolescent idiopathic scoliosisCosmetic parametersQuality of life

Identifiers

PMID41615442

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.