Evidence map›Paper›PMID 41615440›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Explant analysis of two rhine cervical discs.

Göksu Kandemir, Paul Rushton, Thomas Joyce, Chris Kellett

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Göksu KandemirNewcastle University, Newcastle upon Tyne, UK. goksu.kandemir@ncl.ac.uk.
Paul RushtonGreat North Children's Hospital, Newcastle upon Tyne, UK.
Thomas JoyceNorthumbria University, Newcastle upon Tyne, UK.
Chris KellettLeeds General Infirmary, Leeds, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCervical disc replacement aims to preserve cervical spine motion and reduce the risk of adjacent segment disease. The Rhine cervical disc is a non-articulating, viscoelastic implant designed to replicate the natural biomechanics of the cervical spine. To date, no explant analyses of this device have been published. This study presents the explant analysis of two Rhine cervical discs retrieved from a 41-year-old female patient who had undergone two-level cervical total disc replacement, C4-C5 and C6-C7, for myeloradiculopathy.

methodsThe implants were removed approximately one year after the surgery due to increasing neck discomfort, recurrent neurological symptoms, and radiographic evidence of osteolysis. Explant analysis was performed on both implants to assess their physical condition and any associated tissue reactions.

resultsBoth explants were intact, however, notable findings included plastic deformation of the viscoelastic cores, particularly in the upper disc. The direction of shear deformation differed between the explants, anterior in the upper disc and posterior in the lower disc, suggesting asymmetric loading conditions. In addition, osteolysis was observed predominantly at the posterior aspect of the lower disc one year after implantation.

conclusionThese observations highlight deformation of the viscoelastic core in Rhine cervical discs. Whether this finding relates to surgical factors such as implant sizing and positioning, or to implant design itself, improper sizing and malpositioning may contribute to excessive shear forces, core deformation, and poor clinical outcomes. These factors are all important in implant survival and should be carefully considered. The deformation observed in the cores of the explants is consistent with viscoelastic polymer limitations reported in the literature for other viscoelastic cervical discs.

Indexed as

Cervical VertebraeIntervertebral DiscProstheses and ImplantsRadiculopathyTotal Disc ReplacementAdultBiomechanical PhenomenaFemaleHumansOsteolysisCervical disc replacementCervical spineOsteolysisPlastic deformationViscoelastic

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.