Evidence map›Paper›PMID 41615264›Full record

ArticleVeterinary medicine and science2026

Histological and Immunohistochemical Characterization of a Histiocytic Sarcoma Associated With a Follicular Lymphoma in a Ring-tailed Lemur (Lemur catta).

Nicolás Aradilla, Rocío Canales, Teresa Lorenzo-Bermejo, Mireia Mainez, Jordi Aguiló-Gisbert, David Marbella, Javier María De Pablo-Moreno, Antonio Rodríguez-Bertos

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In one paragraph

Article in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nicolás AradillaVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.ORCID https://orcid.org/0009-0007-6149-0591
Rocío CanalesMundomar Veterinary Services, Benidorm, Spain.
Teresa Lorenzo-BermejoDepartment of Biomedical Sciences, Faculty of Health Sciences, CEU Cardenal Herrera University, CEU Universities, Valencia, Spain.ORCID https://orcid.org/0009-0003-3830-216X
Mireia MainezLa Marina Exotics Veterinary Center, Elche, Spain.
Jordi Aguiló-GisbertVeterinary Clinical Hospital, CEU Cardenal Herrera University, CEU Universities, Valencia, Spain.
David MarbellaVeterinary Clinical Hospital, CEU Cardenal Herrera University, CEU Universities, Valencia, Spain.
Javier María De Pablo-MorenoVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.ORCID https://orcid.org/0009-0008-1299-2592
Antonio Rodríguez-BertosVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.ORCID https://orcid.org/0000-0001-9543-313X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 20-year-old neutered male ring-tailed lemur (Lemur catta) diagnosed with an intrathoracic mass died during surgical excision. Morphological characteristics of the mass during necropsy were consistent with a mediastinal abscess in the left hemithorax. Histological examination identified a disseminated histiocytic sarcoma involving spleen, kidneys, multiple lymph nodes, diaphragm and parietal pleura, as well as a concurrent follicular lymphoma in a separate lymph node. A mixed metastatic infiltrate composed of both neoplasms was found within the capsule of the intrathoracic abscess. Immunohistochemical analysis (Iba-1, CD3, PAX-5, IRF-4, pancytokeratin AE1/AE3 and Ki-67) confirmed both neoplasms and revealed mild IRF-4 immunoreactivity for histiocytic sarcoma cells. The histomorphologic and immunohistochemical features of the histiocytic sarcoma in this Lemur catta were characteristic of this condition in other species. This report documents the first case of histiocytic sarcoma in Lemur catta, providing novel histopathological and immunohistochemical insights of this condition in prosimians.

Indexed as

Histiocytic SarcomaLemurLymphoma, FollicularAnimalsImmunohistochemistryMalehistopathologyimmunohistochemicalLemur cattaneoplasiawildlife

Identifiers

PMID41615264
PMCPMC12857495

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.