Evidence map›Paper›PMID 41615197›Full record

ArticleTurkish journal of pharmaceutical sciences2026

Evaluation of Wound Healing Potential of (5-formylfuran-2-yl)Methyl Benzoates by

Mehmet Koca, Fatma Yeşilyurt, Hatice Şükran Durmaz, Ahmet Hacımüftüoğlu, Neslihan Çelebioğlu

Abstract read
In one paragraph

Article in Turkish journal of pharmaceutical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Callus Induction inPlants (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mehmet KocaAtatürk University Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Erzurum, Türkiye.ORCID 0000-0002-8606-2039
Fatma YeşilyurtAtatürk University Health Services Vocational College, Erzurum, Türkiye.ORCID 0000-0002-1336-6322
Hatice Şükran DurmazAtatürk University Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Erzurum, Türkiye.ORCID 0000-0002-8606-2039
Ahmet HacımüftüoğluAtatürk University Faculty of Medicine, Department of Medical Pharmacology, Erzurum, Türkiye.ORCID 0000-0002-9658-3313
Neslihan ÇelebioğluAtatürk University Faculty of Science, Department of Organic Chemistry, Erzurum, Türkiye.ORCID 0000-0003-1882-0720

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: 5-hydroxymethylfurfural (5-HMF) derivatives, found in many natural products, exhibit various biological activities. Benzoate derivatives enhance cellular re-epithelialization without inducing cytotoxicity. This study aimed to evaluate the wound-healing potential of six benzoate derivatives of 5-HMF by usingan Materials and Methods: Six ester derivatives of 5-HMF were synthesized, and the molecular structures were elucidated by proton-1 nuclear magnetic resonance, carbon-13 nuclear magnetic resonance, and Quadrupole time-of-flight mass spectrometry. The effects of the compounds on neuronal and fibroblast cell survival were determined Results: The MTT test showed that M2, M3, M5, and M6 did not damage fibroblasts at any tested concentration (10 Conclusion: M3 and M5 promote cell migration and have the highest potential for wound healing among the compounds tested.

Indexed as

cell migrationcell viability assayEster derivatives of 5-hydroxymethylfurfuraltotal antioxidant capacity

Identifiers

PMID41615197
PMCPMC12862172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.