Evidence map›Paper›PMID 41615163›Full record

ArticlemBio2026

Inhibition of

Samantha A McKeand, Sian E Faustini, Alex Cook, Nikki Kennett, Mark T Drayson, Adam F Cunningham, Ian R Henderson, Christoph M Tang, Jonathan D C Ross, Jeffrey A Cole and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Samantha A McKeandInstitute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0001-5579-7422
Sian E FaustiniInstitute of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom.
Alex CookThe Binding Site, Birmingham, United Kingdom.
Nikki KennettThe Binding Site, Birmingham, United Kingdom.
Mark T DraysonInstitute of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom.
Adam F CunninghamInstitute of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0003-0248-964X
Ian R HendersonInstitute for Molecular Bioscience, University of Queensland, St. Lucia, Queensland, Australia.ORCID 0000-0002-9954-4977
Christoph M TangSir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-8366-3245
Jonathan D C RossSexual Health and HIV, University Hospitals Birmingham, Birmingham, United Kingdom.
Jeffrey A ColeInstitute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom.
Amanda E Rossiter-PearsonInstitute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0002-8567-7998

Funding

Wellcome Trust 108876/B/15/ZWellcome Trust 214374/Z/18/Z
6 · The paper itself

Abstract

Excessive binding of antibodies to the bacterial cell surface can paradoxically increase resistance of some Gram-negative pathogens to complement-mediated killing (CMK). We examined the CMK of 336 IMPORTANCE: The antigenic variation of

Indexed as

Antibodies, BacterialComplement System ProteinsGonorrheaImmunoglobulin GNeisseria gonorrhoeaeBlood Bactericidal ActivityFemaleHumansMaleAntibodies, BacterialComplement System ProteinsImmunoglobulin Gblocking antibodycomplement-mediated killingNeisseria gonorrhoeaeserum resistance

Identifiers

PMID41615163
PMCPMC12977606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.