Evidence map›Paper›PMID 41615162›Full record

ArticlemBio2026

Disruption of methionine synthesis repressor makes

Yayun Wang, Ryuichi Koga, Minoru Moriyama, Takema Fukatsu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. SymbioticmBio · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yayun Wang *Molecular Biosystems Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.
Ryuichi Koga *Molecular Biosystems Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.ORCID 0000-0003-0903-0364
Minoru MoriyamaMolecular Biosystems Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.ORCID 0000-0003-4369-6477
Takema FukatsuMolecular Biosystems Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.ORCID 0000-0001-5987-2602

Funding

Japan Science and Technology Agency JPMJCR25B4Japan Science and Technology Agency JPMJER1902
6 · The paper itself

Abstract

Degenerative genome evolution is widely found among obligatory bacterial mutualists, as observed in plant-sucking hemipteran insects whose symbiont genomes are highly reduced and specialized for provisioning of essential amino acids. Originally, such symbionts must have been derived from environmental free-living bacteria. It is elusive, however, what evolutionary changes are involved in the early stages of such elaborate mutualistic associations. Here, we addressed this evolutionary question using the experimental symbiotic system consisting of the stinkbug

Indexed as

Escherichia coliEscherichia coli ProteinsHeteropteraMethionineRepressor ProteinsSymbiosisAnimalsEscherichia coli ProteinsMethionineRepressor ProteinsEscherichia coliessential amino acidexperimental evolutionmethioninePlautia stalisymbiosis

Identifiers

PMID41615162
PMCPMC12977542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.