Evidence map›Paper›PMID 41614920›Full record

ArticleCurrent issues in molecular biology2026

Genomic Landscape of Thymic Carcinoma: A Large-Scale Analysis of Somatic Mutations, Demographic Disparities, and Metastatic Drivers from the AACR Project GENIE

Aden V Chudziak, Tyson J Morris, David Maliy, Grace S Saglimbeni, Akaash Surendra, Beau Hsia, Huijun Li, Abubakar Tauseef

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Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aden V ChudziakSchool of Molecular Sciences, Arizona State University, Tempe, AZ 85281, USA.ORCID 0009-0007-0421-0258
Tyson J MorrisDepartment of Hematology and Oncology, Creighton University School of Medicine, Phoenix, AZ 85012, USA.ORCID 0009-0008-1457-591X
David MaliyCollege of Natural Sciences, Grand Canyon University, Phoenix, AZ 85017, USA.ORCID 0009-0002-7476-9325
Grace S SaglimbeniDepartment of Hematology and Oncology, Creighton University School of Medicine, Phoenix, AZ 85012, USA.ORCID 0009-0006-1993-9554
Akaash SurendraSchool of Life Sciences, Arizona State University, Tempe, AZ 85281, USA.ORCID 0009-0006-9693-4829
Beau HsiaDepartment of Hematology and Oncology, Creighton University School of Medicine, Phoenix, AZ 85012, USA.ORCID 0009-0009-6403-502X
Huijun LiDivision of Hematology and Oncology, Department of Internal Medicine, Creighton University Medical Center, Omaha, NE 68124, USA.
Abubakar TauseefDivision of Hematology and Oncology, Department of Internal Medicine, Creighton University Medical Center, Omaha, NE 68124, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thymic carcinoma (TC) is a rare and aggressive malignancy with poor prognosis, and its genomic landscape remains incompletely defined. Identifying the somatic alterations that shape TC biology is essential for improving diagnostic precision, developing targeted therapies, and informing early detection strategies. We performed a retrospective genomic analysis of 141 TC tumor specimens from 134 patients using de-identified data from the American Association for Cancer Research (AACR) Project GENIE

Indexed as

AACR project GENIEcopy number alterationsgenomic landscapemetastasisMTORsex-specific mutationssomatic mutationsthymic carcinomaTP53

Identifiers

PMID41614920
PMCPMC12839660

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.